In‐vivo

Excel templates for in-vivo assays

INVIVO_ALI.xlsx

• mass concentration
• size distribution

INVIVO_BAL.xlsx

• biochem analysis inhalation
• cell counts
• Cellularity

INVIVO_BIODISTRIBUTION.xlsx

• Biodistribution

Exotoxicity INVIVO_ECOTOX.xlsx

• soil - C. Elegans
• water - algae - P.subcap
• water - fish - D Rerio
• water - microalgae - D. Magna

INVIVO_GENOTOX.xlsx

• chromosomal damage in vitro
• COMET
• Micronucleus
• TEM observation

INVIVO_IMMUNOTOX.xlsx

• Blood counts
• Cytokine secretion MPh
• FACS analysis
• NO production
• Polyclonal proliferation
• Serum cytokine
• Serum total antibodies

INVIVO_INHALATION.xlsx

• cytokines levels
• DNA-damage lung
• hystopathology
• mRNA expression in vivo

INVIVO_ORGANBURDEN.xlsx

• MW digestion + ICP-MS

INVIVO_PATTERNDISTRIBUTION.xlsx

• CRM
• IBM
• ToF-SIMS

INVIVO_PBPK.xlsx

• PBPK

INVIVO_PULMONARY.xlsx

• biochemical analysis
• cytokines levels
• DNA-damage lung
• histopathology
• mRNA expression in vivo

INVIVO_TOXLONGTERM.xlsx

• COMET - sistemic genotox
• lung genotoxicity
• Micronuclei - sistemic genotox
• PIG-A sistemic genotox