Search result boosting

Response can be boosted to promote certain types above others.

From Peter Woolard (GSK) & Jean Marc Neefs (JnJ):

UniProt Reviewed Entries (aka Swiss-Prot)

UniProt Unreviewed Entries (aka sptrEMBL)

EnsEMBL Protein Ids

RefSeq proteins (demoted)

(Want to be able to link to and from genes; consider RefSeq)

###Genes

HGNC – not HGMD

Entrez Gene

EnsEMBL genes (promoted)

EnsEMBL transcripts (promoted)

RefSeq mRNAs (demoted from position 3)

(Want to be able to link to and from proteins; consider RefSeq)

###Diseases

MeSH (promoted)

DO (Disease Ontology)

OMIM(demoted)

EFO (Added)

GWAS trait (Added)

DisGeNet

(comment MeSH has the widest coverage, EFO should have many of DO, plus extra terms, it is the core ontology of the CTTV)

###Hierarchies

ChEMBL

ENZYME (E numbers)

GO

###Molecules

ChemSpider

ChEMBL

###Species

NCBI Taxonomy Id as well as the NCBI Taxonomy Label

###Pathway

WikiPathwayID; (WikiPathways includes Reactome)

ReactomeID

KEGG

###Tissues/Celltypes

Brenda Tissue Ontology

EFO