FAE added as subclass

Added FAE as a subclass after further research. The key difference is that FAE is a specialized component of the broader Peyer's patch epithelium, specifically covering the lymphoid follicles and containing unique features like M cells.

src/ontology/uberon-edit.obo

@@ -45,7 +45,7 @@ synonymtypedef: PENDING_REVIEW "expert consultation and attribution required"
 synonymtypedef: SENSU "taxonomic disambiguation"
 synonymtypedef: SYSTEMATIC "a systematic synonym used as the base name for design patterns"
 default-namespace: uberon
-idspace: EFO http://www.ebi.ac.uk/efo/EFO_  
+idspace: EFO http://www.ebi.ac.uk/efo/EFO_ 
 idspace: NIF_Subcellular http://www.neurolex.org/wiki/ 
 idspace: NIFEXT http://uri.neuinfo.org/nif/nifstd/nifext_ 
 treat-xrefs-as-equivalent: AEO
@@ -72992,8 +72992,8 @@ id: UBERON:0003532
 name: hindlimb skin
 def: "A zone of skin that is part of a hindlimb [Automatically generated definition]." [OBOL:automatic]
 synonym: "hind limb skin" EXACT [OBOL:automatic]
-synonym: "lower limb skin" EXACT [FMA:23102]
 synonym: "lower limb skin" EXACT [https://orcid.org/0000-0002-0819-0473]
+synonym: "lower limb skin" EXACT [FMA:23102]
 synonym: "skin of hind limb" EXACT [OBOL:automatic]
 synonym: "skin of hindlimb" EXACT [OBOL:automatic]
 synonym: "skin of lower extremity" EXACT [OBOL:automatic]
@@ -90441,8 +90441,8 @@ intersection_of: part_of UBERON:0005928 ! external naris
 
 [Term]
 id: UBERON:0004693
-name: follicle associated epithelium
-def: "The specialized epithelium of the Peyer's patch." [ISBN:0-8153-1691-7, MGI:cwg, MP:0002388]
+name: Peyer's patch epithelium
+def: "The specialized epithelial layer covering the entire Peyer's patch, including both the follicular and interfollicular areas and forming part of the gut-associated lymphoid tissue." [ISBN:0-8153-1691-7, MGI:cwg, MP:0002388]
 subset: pheno_slim
 synonym: "Peyer's patch epithelium" EXACT [MA:0000731, PMID:31813624]
 xref: EMAPA:36506
@@ -224678,6 +224678,15 @@ relationship: dc-contributor https://orcid.org/0000-0002-4341-3265
 relationship: dc-contributor https://orcid.org/0000-0003-2804-127X ! Sanjay Jain
 property_value: dcterms-date "2024-08-28T16:10:50Z" xsd:dateTime
 
+[Term]
+id: UBERON:8700001
+name: follicle associated epithelium
+def: "A specialized epithelial layer overlying the luminal surface of lymphoid follicles in gut-associated lymphoid tissue. It is found in Peyer's patches of the small intestine and appendix in humans and in the intestine and caecal patches in mice. This layer contains specialised M cells and has fewer goblet cells compared to surrounding tissue. This layer plays a crucial role in mucosal immune surveillance." [DOI: 10.1007/s00702-022-02561-x, DOI: 10.4061/2010/823710]
+synonym: "FAE" EXACT [DOI: 10.1007/s00702-022-02561-x]
+is_a: UBERON:0004693 ! Peyer's patch epithelium
+relationship: dc-contributor https://orcid.org/0009-0005-7919-4905
+property_value: dcterms-date "2024-11-07T11:44:27Z" xsd:dateTime
+
 [Term]
 id: UBERON:8850000
 name: lumen of pulmonary alveolus