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Study the relative contributions of relaxation of purifying selection vs. increase in positive selection, in the observed high sequence divergence of genes from late development.

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Adaptive-evolution-in-late-development-and-adult

Adaptive evolution of animal proteins expressed in late development and adult

  1. We use selection_analysis.R to perform Modularity analysis, Transcriptome index analysis
    and Polygenic selection analysis.
  2. We use module_detection.R to detect modules (different sets of specifically expressed genes (modules) in each developmental period).
  3. Please see https://github.com/CMPG/polysel for detecting positive selection on pathways.

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Study the relative contributions of relaxation of purifying selection vs. increase in positive selection, in the observed high sequence divergence of genes from late development.

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