This repository contains raw and processed data as supplemental material for the paper "A pilot study of cerebral metabolism and serotonin 5HT2A receptor occupancy in rats treated with the psychedelic tryptamine DMT in conjunction with the MAO inhibitor harmine" published in Frontiers in Pharmacology.
DOI: 10.3389/fphar.2023.1140656
The repo contains three folders (and subfolders) that each contain raw and analysed data from one methodological approach used in the experiments.
In general, each folder contains an Analysis/Scripts subfolder with scripts that can be used in ascending order to recreate the data analysis and plots and figures presented in the paper. Note: 03_KETANSERIN_and_MHMZ_DATA does not contain these subfolders, but contains the scripts directly. All Scripts are also stored as HTML files in the corresponding HTML_files subfolders.
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01_brain_concentration_data contains data of DMT, harmine and metabolite concentrations that were collected ex vivo for both experiments.
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02_FDG_PET_data contains FDG-PET data from the first experiment.
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03_KETANSERIN_and_MHMZ_DATA contains 5HT2A receptor occupancy data from both experiments (DMT vs. ketanserin in experiment 1 and DMT vs. MH.MZ in experiment 2).