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Find codon point mutations that cause a specific amino acid substitution.

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PoSub

A command line tool for finding codon point mutations that cause a specific amino acid substitution.

Inputs:

  • Starting codon (3 letter string)
  • Desired amino acid substitution (single letter, stop codon = "X")
  • Optional: codon position for point mutation

A basic query:

python posub.py TCG L

A query with position argument:

python posub.py GAC E -p 3

Use the -v argument for more text output.

Tested for Python 2.7 and Python 3.5

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Find codon point mutations that cause a specific amino acid substitution.

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