This repository contains a simple linear pipeline for the analysis of volume series output by heterogeneity software designed for the anlayis of single-particle Cryo-EM samples. It is based on Singular Value Decomposition (SVD) of a series volumes, as well as an inspection of power power spectrum across the series.
Details about CryoSVD construction can be found in the associated publication
The data necessary to run the compare_volume_series.ipynb notebook can be found on zenodo.
git clone [email protected]/flatironinstitute/cryosvdconda create -n cryosvd python=3.10conda activate cryosvdcd cryosvdpip install .- Run the
compare_volume_series.ipynbjupyter notebook.