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Jadecoool committed Oct 5, 2024
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11 changes: 10 additions & 1 deletion .github/data-storage/projections_db.json
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{
"model": "TestModel",
"changes": [
"model-output/ISI-TestModel/2024_2025_1_FLU-ISI-TestModel.parquet"
"model-output/ISI-TestModel/2024_2025_1_FLU-ISI-TestModel.parquet",
"model-output/ISI-TestModel/2024_2025_1_COVID-ISI-TestModel.parquet"
]
},
{
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"model-output/OptimAgent-GEMS/2024_2025_1_COVID-OptimAgent-GEMS.parquet"
]
}
],
"safinea": [
{
"model": "FLUmodel",
"changes": [
"model-output/safinea-FLUmodel/2024_2025_1_FLU-safinea-FLUmodel.parquet"
]
}
]
}
10 changes: 5 additions & 5 deletions Readme.md
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# RespiCompass - European Respiratory Diseases Scenario Hub
# RespiCompass - ECDC's Respiratory Diseases Scenario Hub
![RespiCompass Logo](https://github.com/european-modelling-hubs/RespiCompass/blob/main/respicompass_logo.png)

Details on current rounds can be found at:
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With many uncertain factors at play, it is challenging to predict respiratory virus burden in forthcoming winter seasons. However, by combining data from national surveillance systems with published scientific evidence, expert knowledge, and leveraging expertise from global modelling groups, this respiratory disease scenario modelling hub provides public health advisors and policy decision-makers at European, national, or subnational level with robust insights into plausible winter season scenarios. This hub provides guidance—a "compass"—to support public health stakeholders in their long-term planning and anticipatory action. Secondly, such a hub builds a synergistic community of policy advisors, policy makers and modellers and brings modelling closer to decision making.

## How to Join RespiCompass
RespiCompass welcomes teams willing to contribute their projections. Detailed information on how to join are provided in the [Wiki](https://github.com/european-modelling-hubs/RespiCompass/wiki). Here’s a concise guide on how to participate:
RespiCompass welcomes Modelling teams willing to contribute their projections. Detailed information on how to join are provided in the [Wiki](https://github.com/european-modelling-hubs/RespiCompass/wiki). Here’s a concise guide on how to participate:

1. **Create a Metadata File**:
1. **Create a metadata file**:
- Include key information about your team and model.
- read more [detailed instructions to create a metadata file](https://github.com/european-modelling-hubs/RespiCompass/wiki/Metadata).

2. **Develop Your Model and model projections**:
2. **Develop your model and model projections**:
- Develop your model and produce projections. We value diverse model approaches and implementations.
- Ensure your projections respect the provided scenario assumptions (refer to specific rounds information).

3. **Submit Model Projections**:
3. **Submit model projections**:
- Follow the [submission format guidelines](https://github.com/european-modelling-hubs/RespiCompass/wiki/Submission-format).
- Submit your projections by following the [instructions to open a pull request on GitHub](https://github.com/european-modelling-hubs/RespiCompass/wiki/Submitting-using-GitHub-Website).

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4 changes: 2 additions & 2 deletions hub-config/tasks.json
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]
}
],
"submissions_due": {"start":"2024-04-14","end":"2024-10-03"}
"submissions_due": {"start":"2024-04-14","end":"2024-10-09"}
},
{
"round_id_from_variable": true,
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]
}
],
"submissions_due": {"start":"2024-04-14","end":"2024-10-03"}
"submissions_due": {"start":"2024-04-14","end":"2024-10-09"}
}
],
"output_type_id_datatype": "character"
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5 changes: 3 additions & 2 deletions round1_2425_covid.md
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Waning immunity estimates from studies considered to define scenario assumptions are reported [here](https://docs.google.com/document/d/1MthtD6EWm4UWsjJttNUKYHP-O9oLqSv2vAXL-1aHXFA/edit?usp=sharing).

#### COVID-19 Vaccine Effectiveness
For all scenarios we assume a VE against infection of 50% few days after inoculation in line with recent studies. We assume a VE against hospitalisation few days after inoculation of 75%, compatible with recent studies. Importantly, this VE against hospitalisation reflects the combined effects of protection against both infection and hospitalisation in the event of a breakthrough infection. The provided VE against hospitalisations represents the overall protection, which has two contributions: one from protection against infection, and the other from protection against severe outcomes, such as hospitalisation, if infection occurs. For this round we assume the same VE for all age groups.
For all scenarios we assume a VE against infection of 50% few days after inoculation in line with recent studies. We assume a VE against hospitalisation few days after inoculation of 75%, compatible with recent studies. Importantly, this VE against hospitalisation is defined as the reduction in hospitalisation risk of recently vaccinated individuals versus individuals without recent vaccination. This VE is not conditional on being infected. Mathematically, this VE is the combined effect of vaccine protection against infection (VE_S) and protection against hospitalisation in case of breakthrough infection (VE_H): VE = 1 - (1 - VE_S) * (1 - VE_H). In the optimistic waning scenario, no waning of severe VE means that VE_H remains the same, while VE_S (and therefore the combined VE) wanes. For this round we assume the same VE for all age groups.
Teams may, at their discretion, include additional effects of vaccines, such as the reduced infectiousness of vaccinated individuals if they become infected.

VE estimates from studies considered to define scenario assumptions are reported [here](https://docs.google.com/document/d/1XdbVyWbehuqqa2qdu7028tWh7UGCSP2V-opsp4F83fo/edit?usp=sharing). It is important to note that these VE estimates are based on individuals who received an updated vaccine in the past season, compared to those who did not. Therefore, the VE is not being assessed against a completely vaccine-naive population.
VE estimates from studies considered to define scenario assumptions are reported [here](https://docs.google.com/document/d/1XdbVyWbehuqqa2qdu7028tWh7UGCSP2V-opsp4F83fo/edit?usp=sharing). It is important to note that these VE estimates are based on individuals who received an updated vaccine in the studied season, compared to those who did not. Therefore, the VE is not being assessed against a completely vaccine-naive group. Modelling teams should make judgment calls on modelling and informing vaccine effectiveness relative to naive individuals.

#### Vaccine Coverage
In scenarios A and B, we assume vaccination coverage for the 60+ age group is 15% higher compared to the data reported during the 2023/2024 winter season. This represents a relative increase, meaning that a past coverage of 50% would increase to 57.5%.
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- We leave the implementation of the vaccination rollout to the discretion of the teams. This includes decisions on whether to use constant or time-varying administration rates and whether to administer most doses before the respiratory disease season
- Functional shape of waning immunity against infection and against severe outcomes (following the specified decrease of immunity against infection within the specified time frame).
- Impact of seasonality, including seasonal behavioural changes.
- VEs against other endpoints and VEs relative to immune naive individuals.


### Data
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2 changes: 1 addition & 1 deletion round1_2425_influenza.md
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#### Vaccine Effectiveness (VE)
For all scenarios we assume a VE = 40% against symptomatic infection based on available literature (see [here](https://docs.google.com/document/d/1RKkT9aYD5D8tsRYE1-jQ1jUDhckEWxIhMQ9plO1dk_c/edit?usp=sharing) for list of studies considered). For this round we assume the same VE for all age groups.
Teams may, at their discretion, include additional effects of vaccines, such as the reduced infectiousness of vaccinated individuals if they become infected. Teams can model waning of vaccine-induced protection at their discretion. It is important to note that these VE estimates are based on individuals who received an updated vaccine in the past season, compared to those who did not. Therefore, the VE is not being assessed against a completely naive population.
Teams may, at their discretion, include additional effects of vaccines, such as the reduced infectiousness of vaccinated individuals if they become infected. Teams can model waning of vaccine-induced protection at their discretion. It is important to note that these VE estimates are based on individuals who received an updated vaccine in the studied season, compared to those who did not. Therefore, the VE is not being assessed against a completely naive population.

#### Vaccine Coverage and Rollout
In scenarios A and B, we assume vaccination coverage for the 65+ age group is 15% higher compared to the data reported during the last season for which data is available (2021/2022 for most of the countries). This represents a relative increase, meaning that a coverage of 50% would increase to 57.5%.
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