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haowang-bioinfo committed Mar 11, 2023
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This directory contains datasets that were used for the generation and curation of Fruitfly-GEM. The files and their contents are briefly summarized below.


- `human2FruitflyOrthologs.json`: The human-fruit fly ortholog pairs downloaded from the [Alliance of Genomes Resources](https://www.alliancegenome.org).
- `human2FruitflyOrthologs.tsv`: The human-fruit fly ortholog pairs downloaded from the [Alliance of Genomes Resources](https://www.alliancegenome.org) using the following code:
```bash
curl -X \
GET "https://www.alliancegenome.org/api/homologs/9606/7227?filter.stringency=stringent&limit=50000&page=1" \
-H "accept: application/json" | \
jq -r \
'["fromGeneId", "fromSymbol", "toGeneId", "toSymbol", "best",
"bestReverse", "methodCount", "totalMethodCount"], (.results[] |
[.gene["id"], .gene["symbol"], .homologGene["id"], .homologGene["symbol"],
.best, .bestReverse, .methodCount, .totalMethodCount])
| @tsv' > human2FruitflyOrthologs.tsv
```
- `fruitflySpecificMets.tsv` and `fruitflySpecificRxns.tsv`: The curated metabolic network that is not part of human metabolism but specific to fruit fly.


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