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for samples with a low read depth, it can happen that no SNP/variant is found per sample and the
vaf
column inrc_af
contains only NAs.This causes problems in
cor.test()
codeline with one argument only containing NAs when iterating over allparallel::mclapply(seq_along(rc_af), function(idx)
codeline-> simple fix with filtering beforehand for only selected samples containing SNPS which passed the
min_depth
requirement. also include output information about samples which have been ignored (also this could theoretically extracted by the user from the difference ofSNP_readcounts$BAM
andcolnames(AF_table)
but makes it clearer)feel free to edit, was only a fast easy fix,
it is a really nice method