- This repository contains all codes used to analyse the data reported in "Regulatory Mechanisms Orchestrating Cellular Diversity in Cd36+ Olfactory Sensory Neurons Revealed by Single-Cell Multi-omics Analysis".
- https://www.biorxiv.org/content/10.1101/2023.09.21.558403v1
By analyzing single-cell multi-omics data of mature OSNs in the mouse olfactory epithelium, we systematically revealed the transcriptome diversity and spatial distribution of Cd36+ OSNs and found a specific subset of olfactory receptors co-expressed with Cd36 in a deterministic manner, and identified and confirmed Tshz1 as a critical transcription factor that directly promotes Cd36 expression in OSNs through enhancer binding.
- Data is available on the NCBI GEO at Accession number GSE224604.
- Make a new conda environment, e.g.
conda create -n Cd36_OSNs - Activate the environment by
conda activate Cd36_OSNs - Install the specific versions of packages used in this report by
pip install -r requirements.txt
- For more details, please consult the methods in our manuscript, post an issue here, or contact the authors ([email protected])