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Repository files navigation

HarmonizomePythonScripts

The file containing all utility functions that are required to run the scripts can be found here: Utility Functions File

The file containing the gene symbol mapping (mapping all gene symbols to up-to-date human symbols) can be found here: Gene Symbol Mapping File

The file containing the gene-ID-to-symbol mappings can be found here: Gene ID to Symbol Mapping File

Resources: 94

Datasets: 210


Resource Data Set Genes Attributes Statistically Significant Associations In Enrichr/Harmonizome Processing Script
ARCHS4 Human Cell Line 23956 127 608457 Enrichr ARCHS4 HCL Script
ARCHS4 Human Tissue 23169 108 500364 Enrichr ARCHS4 HT Script
ARCHS4 Human Kinase 17201 498 140739 Enrichr ARCHS4 HK Script
ARCHS4 Human Transcription Factors 21917 1724 470861 Enrichr ARCHS4 HTF Script
ARCHS4 IDG Focused Genes 18020 352 95958 Enrichr ARCHS4 IDG Script
Achilles Achilles 12279 216 2652264 Enrichr,Harmonizome Achilles Script
Allen Brain Atlas Adult Human Brain (RNA-Sequencing) 18629 100 92925 ABA-AHB-RS Script
Allen Brain Atlas Adult Human Brain (microarray) 17979 414 1115464 Harmonizome ABA-AHB-MA Script
Allen Brain Atlas Adult Mouse Brain (RNA-Sequencing) 14248 2170 3091165 Harmonizome ABA-AMB-RS Script
Allen Brain Atlas Aging Human Brain (RNA-Sequencing) Dementia TBI - Tissue 27858 32 55716 ABA-AB-D-TBI Script
Allen Brain Atlas Aging Human Brain (RNA-Sequencing) No Disease 28206 40 56388 ABA-AB-NS Script
Allen Brain Atlas Developing Human Brain (RNA-Sequencing) Age 22411 31 44822 ABA-DB-RS-A Script
Allen Brain Atlas Developing Human Brain (RNA-Sequencing) Sample 15072 524 1183125 Harmonizome ABA-DB-RS-S Script
Allen Brain Atlas Developing Human Brain (RNA-Sequencing) Tissue 22411 26 44822 ABA-DB-RS-T Script
Allen Brain Atlas Developing Human Brain (microarray) Age 16827 27 27015 ABA-DB-MA-A Script
Allen Brain Atlas Developing Human Brain (microarray) Sample 17237 492 1270929 Harmonizome ABA-DB-MA-S Script
Allen Brain Atlas Developing Human Brain (microarray) Tissue 16827 26 33653 ABA-DB-MA-T Script
Allen Brain Atlas Prenatal Human Brain (microarray) Sample 19281 1198 1156878 ABA-P-S Script
Allen Brain Atlas Prenatal Human Brain (microarray) Tissue 18947 516 1464840 Harmonizome ABA-P-T Script
Biocarta Pathways 1397 254 4509 Enrichr,Harmonizome Biocarta Script
BioGPS Cell Line 12628 93 172238 Harmonizome BGPS-CL Script
BioGPS Human Cell Type and Tissue 16379 84 205445 Harmonizome BGPS-HT Script
BioGPS Mouse Cell Type and Tissue 15437 74 170878 Harmonizome BGPS-MT Script
BioPlanet ABCA transporters in lipid homeostasis 9813 1510 Enrichr BioPlanet Scripts
BioPlex BioPlex 10271 3915 111694 Enrichr BPLX Script
bgee Human Sample 34668 1077 14983142 BHS Script
bgee Human Developmental Stage 34668 33 603839 BHDS Script
bgee Human Anatomical Entity 34668 308 4308050 BHAE Script
bgee Mouse Sample 16289 10797 9141706 BMS Script
bgee Mouse Developmental Stage 16289 58 660778 BMDS Script
bgee Mouse Anatomical Entity 16289 3142 3163055 BMAE Script
bgee Rat Sample 15799 11 139136 BRS Script
bgee Rat Developmental Stage 15799 2 22100 BRDS Script
bgee Rat Anatomical Entity 15799 10 132835 BRAE Script
CCLE Cell Line CNV Profiles 23261 1040 1144858 Harmonizome CCLE CNV Script
CCLE Cell Line Gene Expression Profiles 18022 1035 749551 Enrichr,Harmonizome CCLE Script
CCLE Cell Line Gene Mutation Profiles 1667 904 105921 Harmonizome CCLE Mut Script
CCLE Cell Line Proteomics 8959 375 122408 Enrichr,Harmonizome CCLE Prot Script
CellMarker Gene-Cell Type Associations 13607 7217 65978 Enrichr,Harmonizome CellMarker Script
ChEA Transcription Factor Targets 2014 21240 353 447756 Enrichr,Harmonizome ChEA 14 Script
ChEA Transcription Factor Targets 2015 21220 199 386625 Enrichr,Harmonizome ChEA 15 Script
ChEA Transcription Factor Targets 2022 17962 757 917047 Enrichr,Harmonizome ChEA 22 Script
Chip Atlas Chip Atlas 18539 963 1361218 CHPATLS Script
ClinVar ClinVar 2458 3291 3638 Enrichr,Harmonizome ClinVar Script
CMAP CMAP 12148 6100 1201897 Enrichr,Harmonizome CMAP Script
CORUM CORUM 2799 2075 9015 Enrichr,Harmonizome CORUM Script
CTD Gene Chemical Interactions 11125 9516 124344 Harmonizome CTD-GCI Script
CTD Gene Disease Interactions 17252 5218 888474 Harmonizome CTD-GDI Script
dbGAP dbGAP 5668 510 12769 Enrichr,Harmonizome dbGAP Script
DeepCoverMOA Drug Mechanisms of Action 7742 874 173741 Enrichr,Harmonizome DeepCoverMOA Script
DepMap CRISPR Gene Dependency 15946 1095 697098 Enrichr,Harmonizome DepMap CRISPR Script
DEPOD Substrates of Phosphatases 293 112 819 Harmonizome DEPOD Script
DisGeNET Gene-Disease Associations 15960 15709 652358 Enrichr,Harmonizome DisGeNET D Script
DisGeNET Gene-Phenotype Associations 14002 6832 196561 Harmonizome DisGeNET P Script
Drugbank Drug Carrier 61 270 352 DRGBNK-DC Script
Drugbank Drug Enzyme 261 869 2429 DRGBNK-DE Script
Drugbank Drug Target 2368 4928 15261 Harmonizome DRGBNK-DT Script
Drugbank Drug Transporter 154 609 1784 DRGBNK-DTRS Script
DSigDB Computational Drug Signatures 18215 15819 293199 DSigDB-CDS Script
DSigDB FDA Approved Drugs 1279 1205 12571 DSigDB-FAD Script
DSigDB Kinase Inhibitors 404 1150 16240 DSigDB-KI Script
DSigDB Perturbagen Signatures 10933 1163 158860 DSigDB-PS Script
ENCODE Histone Modification Site Profiles 22004 435 4453880 Enrichr,Harmonizome ENCODE-HM SCript
ENCODE Transcription Factors 22449 181 1651393 Enrichr,Harmonizome ENCODE-TF Script
ENCODE Transcription Factors - Binding Sites 22467 1679 8803414 Harmonizome ENCODE-TF-BS Script
ESCAPE ESCAPE 16645 228 212441 Enrichr,Harmonizome ESCAPE Script
GAD Gene-Disease Associations 10697 12774 74928 Harmonizome GAD Script
GAD High Level Gene-Disease Associations 8013 18 28182 Harmonizome HL-GAD Script
GDSC Cell Line Gene Expression Profiles 11704 624 280242 Harmonizome GDSC Script
GeneRIF GeneRIF 15201 91042 2549478 Harmonizome GeneRIF Script
GeneSigDB GeneSigDB 19508 3515 416256 Enrichr,Harmonizome GeneSigDB Script
GEO Diseases 18516 233 139800 Enrichr,Harmonizome GEO Disease Script
GEO Gene perturbations 21050 739 348486 Enrichr,Harmonizome GEO Gene Script
GEO Kinase perturbations 19788 285 171000 Enrichr,Harmonizome GEO Kinase Script
GEO Small Molecules 21332 415 318502 Enrichr,Harmonizome GEO SM Script
GEO Transcription Factor Perturbations 19279 154 150869 Enrichr,Harmonizome GEO TF SCript
GEO Viruses 19778 366 222662 Enrichr,Harmonizome GEO Virus Script
GlyGen Glycosylated Proteins 2231 1910 20486 Enrichr,Harmonizome GlyGen Script
GO Biological Processes 2015 15717 13212 969303 Enrichr,Harmonizome GO-BP Script
GO Biological Processes 2023 14811 12318 198050 Enrichr,Harmonizome GO-BP-23 Script
GO Cellular Components 2015 16757 1547 258969 Enrichr,Harmonizome GO-CC Script
GO Cellular Components 2023 11089 926 41883 Enrichr,Harmonizome GO-CC-23 Script
GO Molecular Functions 2015 15777 4162 223181 Enrichr,Harmonizome GO-MF Script
GO Molecular Functions 2023 12478 3851 50339 Enrichr,Harmonizome GO-MF-23 Script
GTEx eQTL 149 7815 149 Harmonizome GTEx eQTL Script
GTEx Sample 19247 2918 8421 Harmonizome GTEx Sample Script
GTEx Tissues 2015 25557 29 112583 EnrichrHarmonizome GTEx Tissue Script
GTEx Tissues 2023 17369 54 108000 Enrichr,Harmonizome GTEx Tissue 23 Script
GTEx Tissue-Specific Aging Signaures 10050 86 26267 Enrichr,Harmonizome GTEx AS Script
Guide to Pharmacology Chemical Ligands of Receptors 899 4893 9376 Harmonizome GTP-CLR Tissue Script
Guide to Pharmacology Protein Ligands of Receptors 187 211 410 Harmonizome GTP-PLR Script
GWAS Catalog GWAS Catalog 4356 1007 8253 Enrichr,Harmonizome GWAS Catalog Script
GWASdb Disease 11804 585 217321 Harmonizome GWASdb Disease Script
GWASdb Phenotype 12487 822 274553 Harmonizome GWASdb Phenotype Script
Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 15144 56 196872 Harmonizome Heiser Script
HMDB Metabolites of Enzymes 5326 22137 845725 Enrichr,Harmonizome HMDB Script
HPA Cell Line Gene Expression Profiles 15372 43 102943 Harmonizome HPA CL Script
HPA Tissue Gene Expression Profiles 17423 31 81082 Harmonizome HPA TG Script
HPA Tissue Protein Expression Profiles 15704 44 138576 Harmonizome HPA TP Script
HPA Tissue Sample Gene Expression Profiles 16657 121 303267 Harmonizome HPA TS SCript
HPM Cell Type and Tissue Protein Expression Profiles 4361 4 4361 Harmonizome HPM SCript
hu.MAP hu.MAP 7669 7669 126176 Enrichr hu.MAP Script
HPO Human Phenotype Ontology 3158 6842 304995 Enrichr,Harmonizome HPO Script
Hub Proteins PPIs 9362 289 58320 Enrichr,Harmonizome Hub Proteins Script
HuBMAP ASCT+B Annotations 1532 1319 5279 Harmonizome ASCT+B Script
HuBMAP Azimuth Cell Type Annotations 3560 1426 13757 Harmonizome Azimuth Script
HuGE Navigator Gene Phenotype Associations 12047 2752 141789 Harmonizome HuGE Navigator Script
HumanCyc Pathways 932 286 1839 Enrichr,Harmonizome HumanCyc Script
IMPC Knockout Mouse Phenotypes 6763 667 36451 Enrichr,Harmonizome KOMP Script
InterPro Predicted Protein Domain Annotations 18002 11015 62614 Enrichr,Harmonizome InterPro Script
Jaspar Predicted Transcription Factor Targets 21372 111 148061 Harmonizome Jaspar Script
Jensen Lab COMPARRTMENTS Curated Protein Localization Evidence Scores 16736 1463 328722 Enrichr,Harmonizome JL-C-CU Script
Jensen Lab COMPARRTMENTS Experimental Protein Localization Evidence Scores 6495 59 91061 Enrichr,Harmonizome JL-C-EX Script
Jensen Lab COMPARRTMENTS Text-mining Protein Localization Evidence Scores 14375 2081 546634 EnrichrHarmonizome JL-C-TM Script
Jensen Lab DISEASES Curated Gene-Disease Association Evidence Scores 2252 770 18144 Enrichr,Harmonizome JL-D-CU Script
Jensen Lab DISEASES Experimental Gene-Disease Association Evidence Scores 4055 350 35164 EnrichrHarmonizome JL-D-EX Script
Jensen Lab DISEASES Text-mining Gene-Disease Association Evidence Scores 1509 4628 832618 Enrichr,Harmonizome JL-D-TM Script
Jensen Lab TISSUES Curated Tissue Protein Expression Evidence Scores 16215 643 357442 Enrichr,Harmonizome JL-T-CU Script
Jensen Lab TISSUES Experimental Tissue Protein Expression Evidence Scores 15505 243 274154 Enrichr,Harmonizome JL-T-EX Script
Jensen Lab TISSUES Text-mining Tissue Protein Expression Evidence Scores 16184 4187 1836577 Enrichr,Harmonizome JL-T-TM Script
KEA Substrates of Kinases 3406 457 12161 Enrichr,Harmonizome KEA Script
KEGG Pathways 3947 200 9324 Enrichr,Harmonizome KEGG Script
Kinase Library Serine Threonine Kinome Atlas 5046 303 303000 Enrichr,Harmonizome KL-ST Script
Kinase Library Tyrosine Kinome Atlas 1457 93 9300 Enrichr,Harmonizome KL-T Script
Klijn et al. Nat. Biotechnol. 2015 Cell Line Gene CNV Profiles 24917 668 2495455 Harmonizome Klijn CNV Script
Klijn et al. Nat. Biotechnol. 2015 Cell Line Gene Expression Profiles 13942 650 1357824 Harmonizome Klijn Expr Script
Klijn et al. Nat. Biotechnol. 2015 Cell Line Gene Mutation Profiles 14367 676 133818 Harmonizome Klijn Mut Script
KnockTF Gene Expression Profiles with Transcription Factor Perturbations 17964 566 105586 Harmonizome KnockTF Script
LINCS Kinativ Kinase Inhibitor Bioactivity Profiles 102 23 149 Harmonizome Kinativ Script
LINCS KinomeScan Kinase Inhibitor Targets 277 71 2057 Enrichr,Harmonizome KinomeScan Script
LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 8347 30970 4184199 Enrichr,Harmonizome L1000 Chem Script
LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 9551 5049 2517262 Enrichr,Harmonizome L1000 CRISPR CS Script
LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 12126 23913 5086167 Enrichr,Harmonizome L1000 Chem CS Script
LOCATE Curated Protein Localization Annotations 9639 78 79181 Harmonizome LOCATE Cur Script
LOCATE Predicted Protein Localization Annotations 19744 24 154683 Harmonizome LOCATE Pred Script
MGI Mouse Phenotype Associations 2015 7798 8579 466673 Enrichr,Harmonizome MGI 15 Script
MGI Mouse Phenotype Associations 2023 12894 10234 201654 Enrichr,Harmonizome MGI 23 Script
miRTarBase miRTarBase 12086 596 37415 Enrichr,Harmonizome miRTarBase Script
MotifMap Predicted Transcription Factor Targets 20429 329 158770 Harmonizome MotifMap Script
MoTrPAC Rat Endurance Exercise Training 8833 160 22075 Enrichr,Harmonizome MoTrPAC Script
MSigDB Cancer Gene Co-expression Modules 4869 356 41327 Enrichr,Harmonizome MSigDB COMP Script
MSigDB Signatures of DEGs for Cancer Gene Perturbations 10764 90 29967 Enrichr,Harmonizome MSigDB GP Script
MW Enzyme Metabolite Associations 1050 734 4921 Harmonizome MW Script
NURSA PPIs 1127 1127 4258 Harmonizome NURSA PPI Script
NURSA Protein Complexes 9783 1796 280542 Enrichr,Harmonizome NURSA Complex Script
OMIM Gene-Disease Associations 4552 6175 6666 Enrichr,Harmonizome OMIM Script
PANTHER Pathways 1962 145 4255 Enrichr,Harmonizome PANTHER Script
Pathway Commons Protein-Protein Interactions 16291 18511 1125042 Harmonizome PCPPI Script
Pathway Commons Pathways 11164 51319 1257932 PCP Script
PFOCR Pathway Figure Associations 2023 13173 35464 307416 Enrichr,Harmonizome PFOCR 23 Script
PFOCR Pathway Figure Associations 2024 14162 54337 445404 Enrichr,Harmonizome PFOCR 24 Script
PheWeb PheWeb 9116 1161 Enrichr PheWeb Scripts
Phosphosite Textmining Biological Term Annotations 2857 882 148171 Harmonizome Phosphosite TM Script
PhosphoSitePlus Substrestes of Kinases 2447 359 6013 Harmonizome PSP Kinase Script
PhosphoSitePlus Phosphosite-Disease Associations 212 140 356 Harmonizome PSP Disease Script
PID Pathways 2510 223 8027 Harmonizome PID Script
ProteomicsDB Cell Type and Tissue Protein Expression Profiles 2776 53 21921 Enrichr,Harmonizome Proteomics DB Script
Reactome Pathways 2014 7535 1638 83680 Enrichr,Harmonizome Reactome 14 Script
Reactome Pathways 2024 11101 2709 125313 Enrichr,Harmonizome Reactome 24 Script
Roadmap Epigenomics Cell and Tissue DNA Methylation 13690 24 49514 Harmonizome Roadmap DNA Script
Roadmap Epigenomics Cell and Tissue Expression 12824 57 109318 Harmonizome Roadmap Epigenomics Script
Roadmap Epigenomics Histone Modification Site Profiles 21031 383 895131 Enrichr,Harmonizome Roadmap HM Script
Sanger Dependency Map Cancer Cell Line Proteomics 8087 949 186983 Harmonizome Sanger Script
SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Drugs 2770 23 5808 Enrichr,Harmonizome SILAC Drug Script
SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Gene Perturbations 203 10 840 Enrichr,Harmonizome SILAC Gene Script
SILAC Phosphoproteomics Signatures of Differentially Phosphorylated Proteins for Protein Ligands 2022 9 5439 Enrichr,Harmonizome SILAC Protein Script
SynGO Synaptic Gene Anntoations 1593 267 3906 Enrichr,Harmonizome SynGO Script
Tabula Sapiens Gene-Cell Associations 8184 469 46900 Enrichr,Harmonizome Tabula Sapiens Script
TargetScan Predicted Conserved microRNA Targets 14923 1537 513997 Enrichr,Harmonizome TargetScanHuman Script
TargetScan Predicted Nonconserved microRNA Targets 18046 1539 627926 Enrichr,Harmonizome TargetScanHuman Script
TCGA Signatures of Differentially Expressed Genes for Tumors 19791 5904 4366695 Harmonizome TCGA Script
TCGA Adrenocortical Carcinoma 18423 79 72970 TCGA-ACC Script
TCGA Bladder Urothelial Carcinoma 18549 430 398197 TCGA-BLCA Script
TCGA Brain Lower Grade Glioma 18480 530 489769 TCGA-LGG Script
TCGA Breast Invasive Carcinoma 18511 1215 1124480 TCGA-BRCA Script
TCGA Cervical squamous cell carcinoma and endocervical adenocarcinoma 18478 309 284538 TCGA-CESC Script
TCGA Cholangiocarcinoma 18589 45 41743 TCGA-CHOL Script
TCGA Colon Adenocarcinoma 18340 501 459393 TCGA-COAD Script
TCGA Esophageal Carcinoma 18875 198 186087 TCGA-ESCA Script
TCGA Glioblastoma Multiforme 18471 173 159910 TCGA-GBM Script
TCGA Head and Neck Squamous Cell Carcinoma 18648 566 527943 TCGA-HNSC Script
TCGA Kidney Chromophobe 18540 91 84676 TCGA-KICH Script
TCGA Kidney Renal Clear Cell Carcinoma 18665 606 565628 TCGA-KIRC Script
TCGA Kidney Renal Papillary Cell Carcinoma 18546 323 299781 TCGA-KIRP Script
TCGA Liver Hepatocellular Carcinoma 18339 423 387737 TCGA-LIHC Script
TCGA Lung Adenocarcinoma 18508 577 533911 TCGA-LUAD Script
TCGA Lung Squamous Cell Carcinoma 18608 552 513287 TCGA-LUSC Script
TCGA Lymphoid Neoplasm Diffuse Large B-cell Lymphoma 18967 48 42973 TCGA-DLBC Script
TCGA Mesothelioma 18545 87 81072 TCGA-MESO Script
TCGA Ovarian Serous Cystadenocarcinoma 18621 429 399505 TCGA-OV Script
TCGA Pancreatic Adenocarcinoma 18493 183 169642 TCGA-PAAD Script
TCGA Pheochromocytoma and Paraganglioma 18370 187 172133 TCGA-PCPG Script
TCGA Prostate Adenocarcinoma 18528 550 509464 TCGA-PRAD Script
TCGA Rectum Adenocarcinoma 18335 177 162528 TCGA-READ Script
TCGA Sarcoma 18584 265 245886 TCGA-SARC Script
TCGA Skin Cutaneous Melanoma 18612 473 439949 TCGA-SKCM Script
TCGA Stomach Adenocarcinoma 18917 453 428467 TCGA-STAD Script
TCGA Testicular Germ Cell Tumors 18742 156 145048 TCGA-TGCT Script
TCGA Thymoma 18514 122 112695 TCGA-THYM Script
TCGA Thyroid Carcinoma 18371 572 525419 TCGA-THCA Script
TCGA Uterine Carcinosarcoma 18821 57 56384 TCGA-UCS Script
TCGA Uterine Corpus Endometrial Carcinoma 18689 581 542785 TCGA-UCEC Script
TCGA Uveal Melanoma 18136 80 73121 TCGA-UVM Script
The Human Protein Atlas Normal Tissue (immunohistochemisty) 9490 108 117708 THPA-NT-I Script
UK BioBank MedicationCategory-Gene Associations 1212 20 2338 Enrichr, UKBioBankGWAS Script
Virus MINT Protein-Viral Protein Interactions 706 185 1140 Harmonizome VM PPI Script
Virus MINT Protein-Virus Interactions 706 68 1036 Enrichr,Harmonizome Virus MINT Script
WikiPathways WikiPathways Pathways 2014 6093 427 22242 Enrichr,Harmonizome WikiPathways 14 Script
WikiPathways WikiPathways Pathaways 2024 8274 880 35588 Enrichr,Harmonizome WikiPathways 2024 Script

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