This suite of software was designed to detect morphological motifs, such as blebs, filopodia, and lamellipodia, from 3D images of surfaces, particularly images of cell surfaces.
It is associated with the paper, Robust and automated detection of subcellular morphological motifs in 3D microscopy images, Nature Methods, 2019, 16, 1037–1044, written by Meghan K. Driscoll, Erik S. Welf, Andrew R. Jamieson, Kevin M. Dean, Tadamoto Isogai, Reto Fiolka, and Gaudenz Danuser.
For more information, please read the User Guide.
Example data is provided here.
Resolved array size error in the Mesh step for Windows.
The software package has been renamed to u-shape3D on the GUI. Please select u-shape3D from the analysis packages list to run the software.
Please refer to the software version available on the uShape3Dpaper branch, which is the version used in the paper by Driscoll et al. (2019).