Opiate vitamin and MME per item

[Maleclypse]

Summary

Content "Opiate Vitamin by MME"

Purpose of change

Vitaminizes opiates. Makes use of the MME model with conversions from this chart. https://medicaid.utah.gov/Documents/files/Opioid-Morphine-EQ-Conversion-Factors.pdf.

Describe the solution

So far I've added comments describing the medicine size and corresponding mme vitamins. Need to add effects and tiers of effects plus excesses.

Describe alternatives you've considered

Adding a multiplier where addiction raises your tolerance by the strength of the addiction.

Testing

Additional context

[Maleclypse]

Goal of this is to further vitaminization of existing medications and improve medicine interaction possibilities.

[Venera3]

Two things:

• The linked table is about oral equivalency, po : iv morphine analgetic potence is about 1 : 3. Since we don't do oral morphine it's pretty minor but you want to bump morphine's vitamin up.
• Heroin is equipotent to morphine but you're not getting medical-grade diamorphine in the US - for anesthetic I went with 50% purity which is already optimistic so I'd go with half of morphine's (fixed) vitamins.

[Maleclypse]

Two things:

• The linked table is about oral equivalency, po : iv morphine analgetic potence is about 1 : 3. Since we don't do oral morphine it's pretty minor but you want to bump morphine's vitamin up.
• Heroin is equipotent to morphine but you're not getting medical-grade diamorphine in the US - for anesthetic I went with 50% purity which is already optimistic so I'd go with half of morphine's (fixed) vitamins.

Do you have any suggestions for the effect tiers or should I just wing it and see how close I am? Also I put in 4x the medically recommended maximum daily dose as the max. Should I go higher than that? I’m aware people can survive more than that in a day but I’m not certain how far of an outlier those instances are.

[Venera3]

Two things:

• The linked table is about oral equivalency, po : iv morphine analgetic potence is about 1 : 3. Since we don't do oral morphine it's pretty minor but you want to bump morphine's vitamin up.
• Heroin is equipotent to morphine but you're not getting medical-grade diamorphine in the US - for anesthetic I went with 50% purity which is already optimistic so I'd go with half of morphine's (fixed) vitamins.

Do you have any suggestions for the effect tiers or should I just wing it and see how close I am? Also I put in 4x the medically recommended maximum daily dose as the max. Should I go higher than that? I’m aware people can survive more than that in a day but I’m not certain how far of an outlier those instances are.

Yeah that's fine - you develop a tolerance to different effects at different rates, so modeling that would be a bother.

An interesting thing you could do with vitamins would be to demonstrate the different kinetics - pkill_slow could have a vitamin that decays into the main opiate at a slow rate. Not necessarily in the same PR, it's just pretty low-hanging and less hardcode is always begfer.

[zachary-kaelan]

The docs say that vitamins with the drug type take 30 minutes to start to take effect, to represent an onset of action through an oral route. Some of these opioids are injected and so should take maybe 3-5 minutes instead.

[Maleclypse]

The docs say that vitamins with the drug type take 30 minutes to start to take effect, to represent an onset of action through an oral route. Some of these opioids are injected and so should take maybe 3-5 minutes instead.

Is that something I need to change in c++? Thanks for catching these.

[zachary-kaelan]

Is that something I need to change in c++? Thanks for catching these.

Unfortunately you might. There is a NO_INGEST flag on the injectables used in the consume_med function in consumption.cpp that appears to skip the consume_effects function which is where the vitamins get added. The drug vitamins appear to be applied in the update_stomach function in character_body.cpp so I'm guessing you'd want to copy the loop in there to the consume_med function.

[Maleclypse]

Is that something I need to change in c++? Thanks for catching these.

Unfortunately you might. There is a NO_INGEST flag on the injectables used in the consume_med function in consumption.cpp that appears to skip the consume_effects function which is where the vitamins get added. The drug vitamins appear to be applied in the update_stomach function in character_body.cpp so I'm guessing you'd want to copy the loop in there to the consume_med function.

You had mentioned on discord you might be up for PRing the c++ against my branch? Unless I'm confusing you with someone. That would be helpful on this at least it would be helpful in getting it further along.

[zachary-kaelan]

You had mentioned on discord you might be up for PRing the c++ against my branch?

Yup, I'm on it.