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Add bam-matcher #84

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Add bam-matcher #84

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@nr23730 nr23730 commented Oct 23, 2023

This PR adds the bam-matcher tool to the variant calling part of the wes protocol.
The tool checks whether both sample are from the same patient.

It works as follows:

  • It comes with three sets of vcf files from the 1k genome project containing germline variants which are all exonic and have high likelihood of switching between REF and ALT alleles (global allele frequency between 0.45 and 0.55). The only difference between them is the number of variants contained within.
  • Performs variant calling on the positions provided by the vcf using GATK HaplotypeCaller
  • Checks whether the mutation is present in both samples
  • Generates a report with a conclusion

As we don't need to differentiate things like subsample or RNAseq data, the code for the conclusion in the pipeline report is a bit more simple.

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