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ScanNeo2 v0.3.0

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@riasc riasc released this 02 Sep 02:01
· 1 commit to main since this release

Features

  • Added sequence similarity filter for MHC-I
    • self-similarity (using kernel similarity)
    • pathogen similarity (BLAST against pathogen-derived epitopes from IEDB)
    • proteome similarity (BLAST against human proteome)
  • Prioritization of neoantigens is now done separately for each variant type (speeds up the process)
  • Update to recent version of ScanExitron (Thanks to @dolittle007)
    • this version updated to recent version of regtools (v0.5.0) - which is available on Conda
    • Singularity/Docker is not necessary anymore
    • Added option to use strand information in exitron calling
  • ScanNeo2 now uses conda environments for all tools (ditched Singularity/Docker)

Fix

  • renamed similarity fields for pathogen and protein to more descriptive names