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Interpretation of predicted mutation effect #64

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TangYiChing opened this issue Sep 26, 2024 · 1 comment
Open

Interpretation of predicted mutation effect #64

TangYiChing opened this issue Sep 26, 2024 · 1 comment

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@TangYiChing
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TangYiChing commented Sep 26, 2024

Hello,

Can you tell me how to interpret the score appropriately?
Does it have a unit, like ΔΔG in kcal/mol?
Is the score comparable?
What is the difference between effects and probability scores?

@LTEnjoy
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LTEnjoy commented Sep 29, 2024

Hi,

The model takes the "wild type sequence" and "mutation information" as input and outputs a "score". A positive score means the mutation is better than the wild type from evolution perspective.

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