diff --git a/Dockerfile b/Dockerfile
index 682f046d4b6ec..c1b6e1bbfe354 100644
--- a/Dockerfile
+++ b/Dockerfile
@@ -218,7 +218,7 @@ FROM vllm-base AS vllm-openai
 
 # install additional dependencies for openai api server
 RUN --mount=type=cache,target=/root/.cache/pip \
-    pip install accelerate hf_transfer 'modelscope!=1.15.0' 'bitsandbytes>=0.44.0' timm==0.9.10
+    pip install accelerate hf_transfer 'modelscope!=1.15.0' 'bitsandbytes>=0.45.0' timm==0.9.10
 
 ENV VLLM_USAGE_SOURCE production-docker-image
 
diff --git a/docs/source/quantization/bnb.rst b/docs/source/quantization/bnb.rst
index 682938cc63d48..84f805bb60c2a 100644
--- a/docs/source/quantization/bnb.rst
+++ b/docs/source/quantization/bnb.rst
@@ -11,7 +11,7 @@ Below are the steps to utilize BitsAndBytes with vLLM.
 
 .. code-block:: console
 
-    $ pip install bitsandbytes>=0.44.0
+    $ pip install bitsandbytes>=0.45.0
 
 vLLM reads the model's config file and supports both in-flight quantization and pre-quantized checkpoint.
 
diff --git a/requirements-test.in b/requirements-test.in
index 57fddb416317e..fb4179c3d8423 100644
--- a/requirements-test.in
+++ b/requirements-test.in
@@ -25,7 +25,7 @@ datamodel_code_generator # required for minicpm3 test
 lm-eval[api]==0.4.4 # required for model evaluation test
 
 # quantization
-bitsandbytes>=0.44.0
+bitsandbytes>=0.45.0
 buildkite-test-collector==0.1.9
 
 numpy < 2.0.0
diff --git a/requirements-test.txt b/requirements-test.txt
index c786a1249bddb..3771577fe8ed0 100644
--- a/requirements-test.txt
+++ b/requirements-test.txt
@@ -37,7 +37,7 @@ audioread==3.0.1
     # via librosa
 awscli==1.35.23
     # via -r requirements-test.in
-bitsandbytes==0.44.1
+bitsandbytes>=0.45.0
     # via -r requirements-test.in
 black==24.10.0
     # via datamodel-code-generator
diff --git a/vllm/model_executor/layers/quantization/bitsandbytes.py b/vllm/model_executor/layers/quantization/bitsandbytes.py
index e01c713dd14db..5dc872933282c 100644
--- a/vllm/model_executor/layers/quantization/bitsandbytes.py
+++ b/vllm/model_executor/layers/quantization/bitsandbytes.py
@@ -145,12 +145,12 @@ class BitsAndBytesLinearMethod(LinearMethodBase):
     def __init__(self, quant_config: BitsAndBytesConfig):
         try:
             import bitsandbytes
-            if bitsandbytes.__version__ < "0.44.0":
+            if bitsandbytes.__version__ < "0.45.0":
                 raise ImportError("bitsandbytes version is wrong. Please "
-                                  "install bitsandbytes>=0.44.0.")
+                                  "install bitsandbytes>=0.45.0.")
         except ImportError as err:
-            raise ImportError("Please install bitsandbytes>=0.44.0 via "
-                              "`pip install bitsandbytes>=0.44.0` to use "
+            raise ImportError("Please install bitsandbytes>=0.45.0 via "
+                              "`pip install bitsandbytes>=0.45.0` to use "
                               "bitsandbytes quantizer.") from err
 
         self.quant_config = quant_config