diff --git a/src/main.ts b/src/main.ts
index 8f38f70..0cbd450 100644
--- a/src/main.ts
+++ b/src/main.ts
@@ -16,18 +16,18 @@ import vClickOutside from 'v-click-outside'
addIcons(HiSolidArrowSmLeft, HiSolidArrowSmRight, RiArrowDropRightLine, RiArrowDropLeftLine)
-const { bind, unbind } = vClickOutside.directive;
+const { bind, unbind } = vClickOutside.directive
const app = createApp(App)
app.directive('click-outside', {
mounted(el, bindling) {
- bind(el, { value: bindling.value });
+ bind(el, { value: bindling.value })
},
beforeUnmount(el) {
- unbind(el);
- },
-});
+ unbind(el)
+ }
+})
app.use(router)
app.use(VueWindowSizePlugin)
app.component('VIcon', OhVueIcon)
diff --git a/src/views/HomeView.vue b/src/views/HomeView.vue
index 673fbdb..cffa713 100644
--- a/src/views/HomeView.vue
+++ b/src/views/HomeView.vue
@@ -8,102 +8,108 @@ const scrollToTop = () => {
- Embrace the Nano Frontier -
-- Unleash the Nano Frontier, where a new era of technology begins. Pioneering advancements - redefine possibilities. Embrace the future with us. -
- +
+ + A BIOMODular Enzyme Delivery Vehicle to Target Biofilms +
++ Presented by the University of British Columbia 2023 Team +
+ + Explore + +The smallest of beginnings
-- Our submission to the biomolecular design competition is a testament to our team's - unwavering commitment to pushing the boundaries of what's possible in the field of - biomolecular engineering. Our project not only addresses a pressing global health - concern but also showcases the immense potential of biomolecular design to provide - innovative solutions to real-world problems. + In our project, numerous considerations had to be taken into account. From selecting the most effective + enzymes for degrading biofilm matrices to crafting precise liposomes using DNA origami templates, our research + journey explores innovative avenues in the battle against antibiotic-resistant bacterial biofilms. + Learn more about the factors that impacted our final design choices.
+ Abstract
-- Lorem ipsum dolor sit amet, consectetur adipiscing elit, sed do eiusmod tempor incididunt - ut labore et dolore magna aliqua. Ut enim ad minim veniam, quis nostrud exercitation - ullamco laboris nisi ut aliquip ex ea commodo consequat. Duis aute irure dolor in - reprehenderit in voluptate velit esse cillum dolore eu fugiat nulla pariatur. Excepteur - sint occaecat cupidatat non proident, sunt in culpa qui officia deserunt mollit anim id - est laborum. -
++ Biofilms are layers of bacterial communities that can adhere to one another within a self-produced matrix. They + can attach to a variety of surfaces including human tissue, causing severe healthcare and environmental issues. + Traditional strategies for combating biofilms include the use of antibiotics and interference of bacterial layer + formation. However, removing biofilms using these methods can be challenging due to antibiotic resistance and + unexpected pathogenic features arising from interference strategies. To address this issue, we aim to create a + modular enzyme delivery vehicle. This structure consists of a DNA-templated liposome, conjugated with variable + enzymes, referred to as an “enzymosome”. By forming our liposomes around DNA-origami structures, which can be + altered to modify their size and shape, we can create a customizable platform. Among the DNA structures + developed – a trigonal bipyramid, pentagonal bipyramid, and octahedron – all three demonstrated high stability + in CanDo©. Future investigations include testing enzyme synergy with liposomes and validation of the platform in + vitro. The modularity of the enzymosome can address biofilms present in various environments such as in cystic + fibrosis patients, food facilities, and water systems. By changing the cargo type and liposome size, this + delivery vehicle provides potential to be used across a wide range of applications. +
+