diff --git a/simulation/differential_mesh/differential_mesh_graph.py b/simulation/differential_mesh/differential_mesh_graph.py
index 9352164..0e44e17 100644
--- a/simulation/differential_mesh/differential_mesh_graph.py
+++ b/simulation/differential_mesh/differential_mesh_graph.py
@@ -8,6 +8,7 @@
 
 import itertools
 from collections.abc import Iterator
+from enum import Enum, auto
 from typing import Any
 
 import matplotlib.pyplot as plt
@@ -30,6 +31,12 @@
 DIFFERENTIAL_MESH_GRAPH_EDGE_COLOR = "#1f78b4"
 
 
+class DifferentialMeshGraphBoundaryCondition(Enum):
+    """Boundary condition enumeration."""
+    REFERENCE_NODE = auto()
+    ZERO_MEAN_NODE_POTENTIAL = auto()
+
+
 class DifferentialMeshGraph:
     """Interface for a differential mesh graph.
 
@@ -282,9 +289,12 @@ def output_spice_netlist(self, netlist: str, target_node: int = -1) -> None:
             f.write(f".print dc v({target_node})\n")
             f.write(".end\n")
 
-    def calculate_node_standard_errors(self,
-                                       noise: float = 1
-                                      ) -> list[tuple[int, int]]:
+    def calculate_node_standard_errors(
+        self,
+        noise: float = 1,
+        boundary_condition: DifferentialMeshGraphBoundaryCondition = (
+            DifferentialMeshGraphBoundaryCondition.REFERENCE_NODE),
+    ) -> list[tuple[int, int]]:
         """Calculates the standard error of the node potentials using
         eigendecomposition.
 
@@ -294,16 +304,38 @@ def calculate_node_standard_errors(self,
         Returns:
             A list of 2-tuples, each consisting of the node label and the
             corresponding standard error.
+
+        Raises:
+            ValueError: If the boundary condition is invalid.
         """
-        node_to_index_map = self.get_node_to_index_map()
-        root_index = node_to_index_map[DIFFERENTIAL_MESH_GRAPH_ROOT_NODE]
         index_to_node_map = self.get_index_to_node_map()
-
         L = self.create_laplacian_matrix()
-        L[root_index, :] = 0
-        L[:, root_index] = 0
-        Linv = np.linalg.pinv(L, hermitian=True)
-        squared_stderrs = np.diag(Linv)
+        match boundary_condition:
+            case DifferentialMeshGraphBoundaryCondition.REFERENCE_NODE:
+                node_to_index_map = self.get_node_to_index_map()
+                root_index = node_to_index_map[
+                    DIFFERENTIAL_MESH_GRAPH_ROOT_NODE]
+
+                L[root_index, :] = 0
+                L[:, root_index] = 0
+                Linv = np.linalg.pinv(L, hermitian=True)
+                squared_stderrs = np.diag(Linv)
+            case DifferentialMeshGraphBoundaryCondition.ZERO_MEAN_NODE_POTENTIAL:
+                eigenvalues, eigenvectors = np.linalg.eigh(L)
+                zero_index = np.argmin(eigenvalues)
+
+                # Remove the zero eigenvalue and its corresponding eigenvector.
+                eigenvectors_squared = eigenvectors**2
+                eigenvectors_squared_without_zero = np.delete(
+                    eigenvectors_squared, zero_index, axis=1)
+                eigenvalues_without_zero = np.delete(eigenvalues, zero_index)
+
+                squared_stderrs = np.sum(eigenvectors_squared_without_zero /
+                                         eigenvalues_without_zero,
+                                         axis=1).T
+            case _:
+                raise ValueError("Invalid boundary condition: %s.",
+                                 boundary_condition)
         return [(index_to_node_map[node_index], np.sqrt(squared_stderr) * noise)
                 for node_index, squared_stderr in enumerate(squared_stderrs)]