diff --git a/CMakeLists.txt b/CMakeLists.txt
index fa268a13ed6..e925614d429 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -305,6 +305,21 @@ if(CMAKE_SYSTEM_NAME STREQUAL "OpenBSD")
   list(APPEND uv_sources src/unix/openbsd.c)
 endif()
 
+if(CMAKE_SYSTEM_NAME STREQUAL "OS400")
+  list(APPEND uv_cflags -Wno-attributes)
+  list(APPEND uv_defines
+       _ALL_SOURCE
+       _LINUX_SOURCE_COMPAT
+       _THREAD_SAFE
+       _XOPEN_SOURCE=500)
+  list(APPEND uv_sources
+       src/unix/aix-common.c
+       src/unix/ibmi.c
+       src/unix/posix-poll.c
+       src/unix/no-fsevents.c
+       src/unix/no-proctitle.c)
+endif()
+
 if(CMAKE_SYSTEM_NAME STREQUAL "OS/390")
   list(APPEND uv_defines PATH_MAX=255)
   list(APPEND uv_defines _AE_BIMODAL)