diff --git a/monailabel/main.py b/monailabel/main.py
index d6b4e80cc..8f692c60f 100644
--- a/monailabel/main.py
+++ b/monailabel/main.py
@@ -62,7 +62,7 @@ def args_start_server(self, parser):
         parser.add_argument("--workers", default=None, type=int, help="Number of worker processes")
         parser.add_argument("--limit_concurrency", default=None, type=int, help="Max concurrent connections")
         parser.add_argument("--access_log", action="store_true", help="Enable access log")
-        parser.add_argument("--root_path", default="/", help="Application root path")
+        parser.add_argument("--root_path", default="", help="Application root path")
         parser.add_argument("--log_level", default="info", help="Log level")
 
         parser.add_argument("-l", "--log_config", default=None, type=str, help="Logging config")
diff --git a/requirements.txt b/requirements.txt
index 69257d0ec..e95a76226 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -13,7 +13,7 @@ monai[nibabel, skimage, pillow, tensorboard, gdown, ignite, torchvision, itk, tq
 uvicorn==0.21.1
 pydantic>=1.10.7,<2.0.0
 python-dotenv==1.0.0
-fastapi==0.95.0
+fastapi==0.110.0
 python-multipart==0.0.9
 httpx==0.23.3
 schedule==1.1.0
diff --git a/setup.cfg b/setup.cfg
index 3a3aabf7d..2165c3a94 100644
--- a/setup.cfg
+++ b/setup.cfg
@@ -39,7 +39,7 @@ install_requires =
     uvicorn==0.21.1
     pydantic>=1.10.7,<2.0.0
     python-dotenv==1.0.0
-    fastapi==0.95.0
+    fastapi==0.110.0
     python-multipart==0.0.9
     requests-toolbelt==0.10.1
     httpx==0.23.3