Issues with adding motifs to multiome dataset: Error in loadFUN(x, seqname, ranges) : trying to load regions beyond the boundaries of non-circular sequence "chr1"

[ptk1601]

I am trying to add motifs to my multiome Signac object, with the mm39 genome and most recent set of GRCm39 annotations. Unfortunately, with the following code:

[email protected] <- "peaks"

add motif information

seqlevelsStyle(BSgenome.Mmusculus.UCSC.mm39) <- "UCSC"

RNA_integrated <- AddMotifs(
object = RNA_integrated,
genome = BSgenome.Mmusculus.UCSC.mm39,
pfm = pfm
)

I am consistently getting this error message: Error in loadFUN(x, seqname, ranges) : trying to load regions beyond the boundaries of non-circular sequence "chr1"

I have tried the aforementioned fix of changing the seqnames to 1-based, but this does not work. Strangely enough, when i revert back to the mm10 genome, I can add motifs without any issue. Is there anything else I can do to fix this? Thank you!