diff --git a/changes/1571.saturation.rst b/changes/1571.saturation.rst
new file mode 100644
index 000000000..4f7732856
--- /dev/null
+++ b/changes/1571.saturation.rst
@@ -0,0 +1 @@
+Loosen saturation unit test to allow DO_NOT_USE
diff --git a/romancal/saturation/tests/test_saturation.py b/romancal/saturation/tests/test_saturation.py
index 6d080af45..ab3f9c28b 100644
--- a/romancal/saturation/tests/test_saturation.py
+++ b/romancal/saturation/tests/test_saturation.py
@@ -83,7 +83,11 @@ def test_read_pattern_saturation_flagging(setup_wfi_datamodels):
     output = flag_saturation(ramp, satmap)
 
     # Make sure that groups after the third get flagged
-    assert np.all(output.groupdq[2:, 5, 5] == group.SATURATED)
+    # To accommodate https://github.com/spacetelescope/stcal/pull/321
+    # this test was loosed to be SATURATED | DO_NOT_USE
+    assert np.all(
+        (output.groupdq[2:, 5, 5] & (group.SATURATED | group.DO_NOT_USE)) != 0
+    )
 
 
 def test_ad_floor_flagging(setup_wfi_datamodels):