diff --git a/pkg/analyze/node_resources.go b/pkg/analyze/node_resources.go
index 7698593df..1f6e62c6f 100644
--- a/pkg/analyze/node_resources.go
+++ b/pkg/analyze/node_resources.go
@@ -8,11 +8,14 @@ import (
 	"strings"
 
 	"github.com/pkg/errors"
-	util "github.com/replicatedhq/troubleshoot/internal/util"
-	troubleshootv1beta2 "github.com/replicatedhq/troubleshoot/pkg/apis/troubleshoot/v1beta2"
-	"github.com/replicatedhq/troubleshoot/pkg/constants"
 	corev1 "k8s.io/api/core/v1"
 	"k8s.io/apimachinery/pkg/api/resource"
+	metav1 "k8s.io/apimachinery/pkg/apis/meta/v1"
+	"k8s.io/apimachinery/pkg/labels"
+
+	"github.com/replicatedhq/troubleshoot/internal/util"
+	troubleshootv1beta2 "github.com/replicatedhq/troubleshoot/pkg/apis/troubleshoot/v1beta2"
+	"github.com/replicatedhq/troubleshoot/pkg/constants"
 )
 
 type AnalyzeNodeResources struct {
@@ -381,13 +384,19 @@ func nodeMatchesFilters(node corev1.Node, filters *troubleshootv1beta2.NodeResou
 
 	// all filters must pass for this to pass
 	if filters.Selector != nil {
-		for k, v := range filters.Selector.MatchLabel {
-			l, found := node.Labels[k]
-			if !found {
-				return false, nil
-			} else if l != v {
-				return false, nil
-			}
+		selector, err := metav1.LabelSelectorAsSelector(
+			&metav1.LabelSelector{
+				MatchLabels:      filters.Selector.MatchLabel,
+				MatchExpressions: filters.Selector.MatchExpressions,
+			},
+		)
+		if err != nil {
+			return false, errors.Wrap(err, "failed to create label selector")
+		}
+
+		found := selector.Matches(labels.Set(node.Labels))
+		if !found {
+			return false, nil
 		}
 	}
 
diff --git a/pkg/analyze/node_resources_test.go b/pkg/analyze/node_resources_test.go
index 87e37327e..204840843 100644
--- a/pkg/analyze/node_resources_test.go
+++ b/pkg/analyze/node_resources_test.go
@@ -3,12 +3,13 @@ package analyzer
 import (
 	"testing"
 
-	troubleshootv1beta2 "github.com/replicatedhq/troubleshoot/pkg/apis/troubleshoot/v1beta2"
 	"github.com/stretchr/testify/assert"
 	"github.com/stretchr/testify/require"
 	corev1 "k8s.io/api/core/v1"
 	"k8s.io/apimachinery/pkg/api/resource"
 	metav1 "k8s.io/apimachinery/pkg/apis/meta/v1"
+
+	troubleshootv1beta2 "github.com/replicatedhq/troubleshoot/pkg/apis/troubleshoot/v1beta2"
 )
 
 func Test_compareNodeResourceConditionalToActual(t *testing.T) {
@@ -501,6 +502,130 @@ func Test_nodeMatchesFilters(t *testing.T) {
 			},
 			expectResult: true,
 		},
+		{
+			name: "true when the label expression matches with operator In",
+			node: node,
+			filters: &troubleshootv1beta2.NodeResourceFilters{
+				Selector: &troubleshootv1beta2.NodeResourceSelectors{
+					MatchExpressions: []metav1.LabelSelectorRequirement{
+						{
+							Key:      "label",
+							Operator: metav1.LabelSelectorOpIn,
+							Values:   []string{"value"},
+						},
+					},
+				},
+			},
+			expectResult: true,
+		},
+		{
+			name: "false when the label expression does not match with operator In",
+			node: node,
+			filters: &troubleshootv1beta2.NodeResourceFilters{
+				Selector: &troubleshootv1beta2.NodeResourceSelectors{
+					MatchExpressions: []metav1.LabelSelectorRequirement{
+						{
+							Key:      "label",
+							Operator: metav1.LabelSelectorOpIn,
+							Values:   []string{"value2"},
+						},
+					},
+				},
+			},
+			expectResult: false,
+		},
+		{
+			name: "true when the label expression matches with operator NotIn",
+			node: node,
+			filters: &troubleshootv1beta2.NodeResourceFilters{
+				Selector: &troubleshootv1beta2.NodeResourceSelectors{
+					MatchExpressions: []metav1.LabelSelectorRequirement{
+						{
+							Key:      "label",
+							Operator: metav1.LabelSelectorOpNotIn,
+							Values:   []string{"value2"},
+						},
+					},
+				},
+			},
+			expectResult: true,
+		},
+		{
+			name: "false when the label expression does not match with operator NotIn",
+			node: node,
+			filters: &troubleshootv1beta2.NodeResourceFilters{
+				Selector: &troubleshootv1beta2.NodeResourceSelectors{
+					MatchExpressions: []metav1.LabelSelectorRequirement{
+						{
+							Key:      "label",
+							Operator: metav1.LabelSelectorOpNotIn,
+							Values:   []string{"value"},
+						},
+					},
+				},
+			},
+			expectResult: false,
+		},
+		{
+			name: "true when the label expression matches with operator Exists",
+			node: node,
+			filters: &troubleshootv1beta2.NodeResourceFilters{
+				Selector: &troubleshootv1beta2.NodeResourceSelectors{
+					MatchExpressions: []metav1.LabelSelectorRequirement{
+						{
+							Key:      "label",
+							Operator: metav1.LabelSelectorOpExists,
+						},
+					},
+				},
+			},
+			expectResult: true,
+		},
+		{
+			name: "false when the label expression matches with operator Exists",
+			node: node,
+			filters: &troubleshootv1beta2.NodeResourceFilters{
+				Selector: &troubleshootv1beta2.NodeResourceSelectors{
+					MatchExpressions: []metav1.LabelSelectorRequirement{
+						{
+							Key:      "label2",
+							Operator: metav1.LabelSelectorOpExists,
+						},
+					},
+				},
+			},
+			expectResult: false,
+		},
+		{
+			name: "true when the label expression matches with operator DoesNotExist",
+			node: node,
+			filters: &troubleshootv1beta2.NodeResourceFilters{
+				Selector: &troubleshootv1beta2.NodeResourceSelectors{
+					MatchExpressions: []metav1.LabelSelectorRequirement{
+						{
+							Key:      "label2",
+							Operator: metav1.LabelSelectorOpDoesNotExist,
+						},
+					},
+				},
+			},
+			expectResult: true,
+		},
+		{
+			name: "false when the label expression does not match with operator DoesNotExist",
+			node: node,
+			filters: &troubleshootv1beta2.NodeResourceFilters{
+				Selector: &troubleshootv1beta2.NodeResourceSelectors{
+					MatchExpressions: []metav1.LabelSelectorRequirement{
+						{
+							Key:      "label",
+							Operator: metav1.LabelSelectorOpDoesNotExist,
+						},
+					},
+				},
+			},
+			expectResult: false,
+		},
 	}
 
 	for _, test := range tests {
diff --git a/pkg/apis/troubleshoot/v1beta2/analyzer_shared.go b/pkg/apis/troubleshoot/v1beta2/analyzer_shared.go
index 297a4163e..0ce3e8f24 100644
--- a/pkg/apis/troubleshoot/v1beta2/analyzer_shared.go
+++ b/pkg/apis/troubleshoot/v1beta2/analyzer_shared.go
@@ -1,6 +1,8 @@
 package v1beta2
 
 import (
+	metav1 "k8s.io/apimachinery/pkg/apis/meta/v1"
+
 	"github.com/replicatedhq/troubleshoot/pkg/multitype"
 )
 
@@ -133,7 +135,8 @@ type NodeResourceFilters struct {
 }
 
 type NodeResourceSelectors struct {
-	MatchLabel map[string]string `json:"matchLabel,omitempty" yaml:"matchLabel,omitempty"`
+	MatchLabel       map[string]string                 `json:"matchLabel,omitempty" yaml:"matchLabel,omitempty"`
+	MatchExpressions []metav1.LabelSelectorRequirement `json:"matchExpressions,omitempty" yaml:"matchExpressions,omitempty"`
 }
 
 type TextAnalyze struct {