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model overfitting #64

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tkisss opened this issue Apr 30, 2024 · 0 comments
Open

model overfitting #64

tkisss opened this issue Apr 30, 2024 · 0 comments

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@tkisss
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tkisss commented Apr 30, 2024

Hi,

I noticed that Pando utilizes regression models like GLM to fit gene expression based on TF expression and chromatin accessibilities without dividing the data into training and test sets. Can I infer that in this scenario, the model is prone to overfitting? Does this strategy provide any benefits for gene expression regulation?
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@tkisss