provide ortholog links for priority fungal pathogens (and ideally make IDs searchable to reach pombe orthologs)

[ValWood]

WHO priority pathogens Oct 2022
source: https://iris.who.int/bitstream/handle/10665/363682/9789240060241-eng.pdf?sequence=1

Priority Level	Pathogen	In PANTHER
Critical	Cryptococcus neoformans	YES
Critical	Candida auris
Critical	Aspergillus fumigatus
Critical	Candida albicans
High	Nakaseomyces glabrata (Candida glabrata)
High	Histoplasma spp.
High	Eumycetoma causative agents
High	Mucorales (e.g., agents causing mucormycosis)
High	Fusarium spp.
High	Candida tropicalis
High	Candida parapsilosis
Medium	Scedosporium spp.
Medium	Lomentospora prolificans
Medium	Coccidioides spp.
Medium	Pichia kudriavzeveii (Candida krusei)
Medium	Cryptococcus gattii
Medium	Talaromyces marneffei
Medium	Pneumocystis jirovecii
Medium	Paracoccidioides spp.

[ValWood]

I put all priorities but we may restrict to Critical/high (or see if there are others people would like)

1. Find out which are in PANTHER and request any exclusions
2. Use PANTHER to provide ortholog data store in Chado
3. Link to UniPort entries in ortholog page section (open website ticket when ready)
4. Make UniProt? IDs searchable in pombe simple search and gene mapper

[ValWood]

using PANTHER directly won't work here
https://pantherdb.org/panther/speciesTree.jsp
because only includes species with a lot of data for transfer in the core trees
We might be able to use PANTHER family IDs from InterPRO though?

[kimrutherford]

Is this related?:

• Potential fungal ortholog links website#2305

[ValWood]

yes, I'll close this. we won't be loading into chado (at least at this stage) but trying to link to a resource that covers the main pathogens.