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Identical annotations from Rodriguez et al #1125

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ValWood opened this issue Nov 10, 2023 · 3 comments
Closed

Identical annotations from Rodriguez et al #1125

ValWood opened this issue Nov 10, 2023 · 3 comments
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@ValWood
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ValWood commented Nov 10, 2023

Screenshot 2023-11-10 at 13 06 34

I don't know if there are more?

CC @manulera

@kimrutherford
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They aren't identical in the PHAF file. They look the same because we're not showing the condition and severity details on the gene pages yet (see pombase/website#2029).

From pombe-embl/external_data/phaf_files/chado_load/htp_phafs/PMID_34984977_phaf.tsv:

Gene systematic ID FYPO ID Condition Severity
SPAC4H3.06 FYPO:0000089 FYECO:0000137,FYECO:0000211(0.005% (v/v)),FYECO:0000334,FYECO:0000005(32C) fitness_log2(-0.0445)
SPAC4H3.06 FYPO:0000089 FYECO:0000137,FYECO:0000211(0.075% (v/v)),FYECO:0000334,FYECO:0000005(32C) fitness_log2(-0.245)

I don't know if there are more?

Yep, there are lots of cases like this. For example SPBC25B2.04c / FYPO:0000087 sensitive to hydrogen peroxide:

image

If we displayed the detail for + H2O2 / FYPO:0000087 ("10mM", "8mM", etc.), it would be obvious what's going on. It would be good to show the matching severity value too.

Gene systematic ID FYPO ID Condition Severity
SPBC25B2.04c FYPO:0000087 FYECO:0000078(2mM),FYECO:0000137,FYECO:0000334,FYECO:0000005(32C) fitness_log2(-0.223)
SPBC25B2.04c FYPO:0000087 FYECO:0000078(4mM),FYECO:0000137,FYECO:0000334,FYECO:0000005(32C) fitness_log2(-0.272)
SPBC25B2.04c FYPO:0000087 FYECO:0000078(6mM),FYECO:0000137,FYECO:0000334,FYECO:0000005(32C) fitness_log2(-0.393)
SPBC25B2.04c FYPO:0000087 FYECO:0000078(8mM),FYECO:0000137,FYECO:0000334,FYECO:0000005(32C) fitness_log2(-0.555)
SPBC25B2.04c FYPO:0000087 FYECO:0000078(10mM),FYECO:0000137,FYECO:0000334,FYECO:0000005(32C) fitness_log2(-0.716)

@manulera
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Yes! not sure if we created an issue to display this info in the website eventually

@kimrutherford
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@ValWood can we close this?

@ValWood ValWood closed this as completed Nov 14, 2023
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