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Interestingly, a SPAC9E9.05 deletion mutant was identified in a screen for mutants that showed negative synthetic growth interac- tion with the cohesion-defective mutants eso1-G799D (Eso1 is the S. pombe ortholog of Esco1/2 and CTF762) and mis4-242 (Mis4 is the S. pombe ortholog of NIPBL63), suggesting that SPAC9E9.05 may be involved in regulation of sister chromatid cohesion64
The text was updated successfully, but these errors were encountered:
Might be a useful disease example:
https://www.pombase.org/reference/PMID:23050226
Interestingly, a SPAC9E9.05 deletion mutant was identified in a screen for mutants that showed negative synthetic growth interac- tion with the cohesion-defective mutants eso1-G799D (Eso1 is the S. pombe ortholog of Esco1/2 and CTF762) and mis4-242 (Mis4 is the S. pombe ortholog of NIPBL63), suggesting that SPAC9E9.05 may be involved in regulation of sister chromatid cohesion64
The text was updated successfully, but these errors were encountered: