diff --git a/index.md b/index.md index 3bf2b36f5..60d4a1170 100644 --- a/index.md +++ b/index.md @@ -78,3 +78,19 @@ You can call `harpy` without any arguments (or with `--help`) to print the docst │ stitchparams Create a template STITCH parameter file │ ╰──────────────────────────────────────────────────────────────╯ ``` + +## Linked-Read Workflow +Depending on your project goals, you may want any combination of SNPs, structural variants (inversions, deletions, duplications), or phased haplotypes. Below is a flow chart +outlining a general workflow of linked-read data. + +```mermaid +graph LR + Demux([demultiplex]):::clean--->QC([QC, trim adapters, etc.]):::clean + QC--->Align([align sequences]):::clean + Align--->SNP([call SNPs]):::clean + SNP--->Impute([impute genotypes]):::clean + SNP--->Phase([phase haplotypes]):::clean + Align--->SV([call structural variants]):::clean + + classDef clean fill:#f5f6f9,stroke:#b7c9ef,stroke-width:2px +``` \ No newline at end of file