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When I tried to number the light chain 'SDIVMTQATSSVPVTPGESVSISCRSSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFGAGTKLEL' in IMGT scheme, it gives me the 1-st CYS at (24, ' '). However, according to the IMGT official website, the 1-st CYS should be at (23, ' '). I'm wondering why this would happen. Also, the conserved TRP and 2-nd CYS are also shifted to (42, ' ') and (105, ' ') which should be (41, ' ') and (104, ' ').
Here is my code:
>> from anarci import number
>> seq = 'SDIVMTQATSSVPVTPGESVSISCRSSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFGAGTKLEL'
>> numbering, chain_type = number(seq, scheme='imgt')
>> numbering
The text was updated successfully, but these errors were encountered:
When I tried to number the light chain 'SDIVMTQATSSVPVTPGESVSISCRSSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFGAGTKLEL' in IMGT scheme, it gives me the 1-st CYS at (24, ' '). However, according to the IMGT official website, the 1-st CYS should be at (23, ' '). I'm wondering why this would happen. Also, the conserved TRP and 2-nd CYS are also shifted to (42, ' ') and (105, ' ') which should be (41, ' ') and (104, ' ').
Here is my code:
The text was updated successfully, but these errors were encountered: