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Constructing wildtype peptides #100

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felixfrenkel opened this issue Jul 12, 2018 · 3 comments
Open

Constructing wildtype peptides #100

felixfrenkel opened this issue Jul 12, 2018 · 3 comments

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@felixfrenkel
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Dear Alex,
Have you tried to use IsoVar to assemble wildtype variants of the mutant peptides?
It seems that now IsoVar is not designed to do that?
Do you have an idea how to tune it to manage it?
Thanx.

@iskandr
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iskandr commented Jun 12, 2019

It wouldn't be hard, can you tell me more about your use case?

@Amfgcp
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Amfgcp commented Jun 13, 2019

If I understand Felix’s question, I would also be interested in the same thing, i.e. outputting the wild-type alongside the mutant peptide.
This is particularly important in the case that the wild-type peptide differs from the ref/annotated peptide due to a germline variant in the vicinity.
Thanks

@iskandr
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iskandr commented Jun 15, 2019

It's on the TODO list but will probably be at least a few weeks before I add the option.

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