From 8f1fd59f7444e146de75429719d6afbf118e53bc Mon Sep 17 00:00:00 2001
From: "Olivia T. Zahn" <42389485+oliviatessa@users.noreply.github.com>
Date: Mon, 19 Dec 2022 10:56:45 -0700
Subject: [PATCH] Update README.md
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Complex networks across many domains (ecological food webs, neural systems, electrical circuits) are made up of statistically significant, subgraphs called network motifs. Network motifs are described by the number of nodes they involve and the nature of the connections in-between the nodes (e.g., directed, or bi-directed). The order of the motif is defined by the number of nodes it involves (i.e. n-order motif involves n+1 nodes). For example, a second-order diverging motif involves 3 nodes:
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A subgraph must be statistically significant over a randomly connected graph to be considered a network motif of a given network. One metric for determining a subgraph’s statistical significance is its z-score when compared to randomly connected graphs.