diff --git a/src/ontology/uberon-edit.obo b/src/ontology/uberon-edit.obo
index b6a65912b8..e44124d3ca 100644
--- a/src/ontology/uberon-edit.obo
+++ b/src/ontology/uberon-edit.obo
@@ -4283,7 +4283,7 @@ xref: UMLS:C0230976 {source="ncithesaurus:Amniotic_Cavity"}
 xref: VHOG:0000855
 xref: Wikipedia:Amniotic_cavity
 is_a: UBERON:0000464 ! anatomical space
-relationship: contains UBERON:0000173 ! amniotic fluid
+relationship: location_of UBERON:0000173 ! amniotic fluid
 relationship: develops_from UBERON:0000087 {source="EHDAA2"} ! inner cell mass
 relationship: develops_from UBERON:0009742 {source="cjm"} ! proamniotic cavity
 relationship: has_quality PATO:0000608 ! closed
@@ -4526,8 +4526,8 @@ xref: Wikipedia:Subarachnoid_space
 intersection_of: UBERON:0000464 ! anatomical space
 intersection_of: adjacent_to UBERON:0002361 ! pia mater
 intersection_of: adjacent_to UBERON:0002362 ! arachnoid mater
-relationship: contains UBERON:0001359 ! cerebrospinal fluid
-relationship: contains UBERON:0001981 {source="ISBN:0471888893"} ! blood vessel
+relationship: location_of UBERON:0001359 ! cerebrospinal fluid
+relationship: location_of UBERON:0001981 {source="ISBN:0471888893"} ! blood vessel
 relationship: part_of UBERON:0010743 ! meningeal cluster
 property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/5/5f/Gray769-en.svg" xsd:anyURI
 property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/f/f8/Gray769.png" xsd:anyURI
@@ -12311,7 +12311,7 @@ xref: ZFA:0001655
 is_a: UBERON:0002323 {source="MA"} ! coelemic cavity lumen
 intersection_of: UBERON:0002553 ! anatomical cavity
 intersection_of: luminal_space_of UBERON:0002406 ! pericardial sac
-relationship: contains UBERON:0002409 ! pericardial fluid
+relationship: location_of UBERON:0002409 ! pericardial fluid
 relationship: develops_from UBERON:0003887 {source="Wikipedia"} ! intraembryonic coelom
 relationship: part_of UBERON:0002406 {source="FMA"} ! pericardial sac
 relationship: present_in_taxon NCBITaxon:7718 {source="PMID:20959416"} ! Ciona
@@ -114844,7 +114844,7 @@ xref: FMA:54721
 xref: neuronames:2359
 xref: SCTID:264194004
 is_a: UBERON:0002553 {source="FMA"} ! anatomical cavity
-relationship: contains UBERON:0000007 ! pituitary gland
+relationship: location_of UBERON:0000007 ! pituitary gland
 relationship: part_of UBERON:0003689 ! sella turcica
 
 [Term]
@@ -133458,7 +133458,7 @@ def: "An organ that contains spermaceti." [Wikipedia:Spermaceti_organ]
 subset: organ_slim
 xref: Wikipedia:Spermaceti_organ
 intersection_of: UBERON:0000062 ! organ
-intersection_of: contains UBERON:0009755 ! spermaceti
+intersection_of: location_of UBERON:0009755 ! spermaceti
 relationship: part_of UBERON:0000033 ! head
 property_value: depicted_by "http://upload.wikimedia.org/wikipedia/commons/3/3b/Sperm_whale_head_anatomy.svg" xsd:anyURI
 
@@ -163821,7 +163821,7 @@ xref: Wikipedia:Virchow-Robin_space
 intersection_of: UBERON:0000464 ! anatomical space
 intersection_of: adjacent_to UBERON:0001981 ! blood vessel
 intersection_of: adjacent_to UBERON:0002361 ! pia mater
-relationship: contains UBERON:0001359 ! cerebrospinal fluid
+relationship: location_of UBERON:0001359 ! cerebrospinal fluid
 relationship: part_of UBERON:0010743 ! meningeal cluster
 property_value: depicted_by "https://static-content.springer.com/image/art%3A10.1007%2Fs11064-015-1581-6/MediaObjects/11064_2015_1581_Fig3_HTML.gif" xsd:anyURI
 
@@ -169454,7 +169454,7 @@ synonym: "fossa ovarica" EXACT LATIN [Wikipedia:Ovarian_fossa]
 xref: FMA:21030
 xref: Wikipedia:Ovarian_fossa
 is_a: UBERON:0000464 ! anatomical space
-relationship: contains UBERON:0000992 ! ovary
+relationship: location_of UBERON:0000992 ! ovary
 relationship: part_of UBERON:0002355 ! pelvic region of trunk
 relationship: part_of UBERON:0005449 ! greater sac
 
@@ -181640,7 +181640,7 @@ synonym: "sinuses of vibrissae" RELATED PLURAL []
 synonym: "upper cavernous sinus" NARROW SENSU []
 synonym: "vibrissa sinus" EXACT []
 is_a: UBERON:0000064 ! organ part
-relationship: contains UBERON:0000178 ! blood
+relationship: has_part UBERON:0000178 ! blood
 relationship: innervated_by UBERON:0001027 ! sensory nerve
 relationship: part_of UBERON:0011933 ! vibrissa unit
 relationship: surrounds UBERON:0011937 ! vibrissa root sheath
@@ -186837,7 +186837,7 @@ xref: FMA:18274
 xref: SCTID:367722009
 intersection_of: UBERON:0000464 ! anatomical space
 intersection_of: luminal_space_of UBERON:0001301 ! epididymis
-relationship: contains UBERON:0006530 {source="FMA"} ! seminal fluid
+relationship: location_of UBERON:0006530 {source="FMA"} ! seminal fluid
 
 [Term]
 id: UBERON:0035957