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Single-cell epigenomic identification of inherited risk loci in Alzheimer’s and Parkinson’s disease

https://www.biorxiv.org/content/10.1101/2020.01.06.896159v1

Bulk ATAC-seq data processing / peak calling

scripts

Differential accessibility analysis with DESeq2 and limma voom

scripts

Single-cell ATAC-seq data processing / peak calling

scripts

LD score regression: Cell type specific analyses

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Colocalization analysis

scripts

SVM model training

scripts

SNP effect scoring with SVMs

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SNP effect interpretation

notebooks

Neural network training

scripts

Neural network interpretation/ variant score visualization

scripts