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updates.md

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Updates:

  • simulate_genotypes.py: Parameters changed for simulation to produce fewer individuals (n_samples=1000, computational speed considerations) but more genotypes (sequence_length=100,000,000 as there were to few common vars generated by original settings)
  • vcf_to_plink.py: Added a hard minor allele frequency threshold of >1% when making plink files. Also added a thinning function to subset to 100k SNPs to speed up downstream epistasis analysis.

TODO:

  • Change color of QQplot to SteelBlue and Indianred
  • Change Bonferroni line to dashed and black
  • Figure out a good facet label for polygenicity
  • delete unused code
  • clean up dependencies and documentation
  • link to poetry documentation