diff --git a/.changelog/40969.txt b/.changelog/40969.txt
new file mode 100644
index 00000000000..cfdcbd7f169
--- /dev/null
+++ b/.changelog/40969.txt
@@ -0,0 +1,3 @@
+```release-note:bug
+resource/aws_elasticache_serverless_cache: Fix `InvalidParameterCombination` error during update
+```
\ No newline at end of file
diff --git a/internal/service/elasticache/serverless_cache.go b/internal/service/elasticache/serverless_cache.go
index c1ffa7b5d09..69838a90af5 100644
--- a/internal/service/elasticache/serverless_cache.go
+++ b/internal/service/elasticache/serverless_cache.go
@@ -340,9 +340,20 @@ func (r *serverlessCacheResource) Update(ctx context.Context, request resource.U
 
 	conn := r.Meta().ElastiCacheClient(ctx)
 
-	if serverlessCacheHasChanges(ctx, new, old) {
-		input := &elasticache.ModifyServerlessCacheInput{}
-		response.Diagnostics.Append(fwflex.Expand(ctx, new, input)...)
+	diff, d := fwflex.Calculate(ctx, new, old)
+	response.Diagnostics.Append(d...)
+	if response.Diagnostics.HasError() {
+		return
+	}
+
+	if diff.HasChanges() {
+		input := elasticache.ModifyServerlessCacheInput{
+			ServerlessCacheName: new.ServerlessCacheName.ValueStringPointer(),
+		}
+		response.Diagnostics.Append(fwflex.Expand(ctx, new, &input, diff.IgnoredFieldNamesOpts()...)...)
+		if response.Diagnostics.HasError() {
+			return
+		}
 		// Unset engine related stuff to prevent the following error:
 		// This API supports only cross-engine upgrades to Valkey engine currently.
 		if new.Engine.Equal(old.Engine) {
@@ -351,11 +362,8 @@ func (r *serverlessCacheResource) Update(ctx context.Context, request resource.U
 		if new.MajorEngineVersion.Equal(old.MajorEngineVersion) {
 			input.MajorEngineVersion = nil
 		}
-		if response.Diagnostics.HasError() {
-			return
-		}
 
-		_, err := conn.ModifyServerlessCache(ctx, input)
+		_, err := conn.ModifyServerlessCache(ctx, &input)
 
 		if err != nil {
 			response.Diagnostics.AddError(fmt.Sprintf("updating ElastiCache Serverless Cache (%s)", new.ID.ValueString()), err.Error())
@@ -596,12 +604,3 @@ type endpointModel struct {
 	Address types.String `tfsdk:"address"`
 	Port    types.Int64  `tfsdk:"port"`
 }
-
-func serverlessCacheHasChanges(_ context.Context, plan, state serverlessCacheResourceModel) bool {
-	return !plan.CacheUsageLimits.Equal(state.CacheUsageLimits) ||
-		!plan.DailySnapshotTime.Equal(state.DailySnapshotTime) ||
-		!plan.Description.Equal(state.Description) ||
-		!plan.UserGroupID.Equal(state.UserGroupID) ||
-		!plan.SecurityGroupIDs.Equal(state.SecurityGroupIDs) ||
-		!plan.SnapshotRetentionLimit.Equal(state.SnapshotRetentionLimit)
-}
diff --git a/internal/service/elasticache/serverless_cache_test.go b/internal/service/elasticache/serverless_cache_test.go
index 90770c03e1c..a4a49ddfc5c 100644
--- a/internal/service/elasticache/serverless_cache_test.go
+++ b/internal/service/elasticache/serverless_cache_test.go
@@ -201,6 +201,46 @@ func TestAccElastiCacheServerlessCache_fullRedis(t *testing.T) {
 	})
 }
 
+func TestAccElastiCacheServerlessCache_redisUpdateWithUserGroup(t *testing.T) {
+	ctx := acctest.Context(t)
+	if testing.Short() {
+		t.Skip("skipping long-running test in short mode")
+	}
+
+	rName := sdkacctest.RandomWithPrefix(acctest.ResourcePrefix)
+	resourceName := "aws_elasticache_serverless_cache.test"
+	var serverlessElasticCache awstypes.ServerlessCache
+
+	resource.ParallelTest(t, resource.TestCase{
+		PreCheck:                 func() { acctest.PreCheck(ctx, t) },
+		ErrorCheck:               acctest.ErrorCheck(t, names.ElastiCacheServiceID),
+		ProtoV5ProviderFactories: acctest.ProtoV5ProviderFactories,
+		CheckDestroy: resource.ComposeAggregateTestCheckFunc(
+			testAccCheckServerlessCacheDestroy(ctx),
+		),
+		Steps: []resource.TestStep{
+			{
+				Config: testAccServerlessCacheConfig_redisUpdateWithUserGroup(rName, "test description"),
+				Check: resource.ComposeAggregateTestCheckFunc(
+					testAccCheckServerlessCacheExists(ctx, resourceName, &serverlessElasticCache),
+					acctest.CheckResourceAttrRegionalARNFormat(ctx, resourceName, names.AttrARN, "elasticache", "serverlesscache:{name}"),
+					resource.TestCheckResourceAttr(resourceName, names.AttrName, rName),
+					resource.TestCheckResourceAttr(resourceName, names.AttrDescription, "test description"),
+				),
+			},
+			{
+				Config: testAccServerlessCacheConfig_redisUpdateWithUserGroup(rName, "test description updated"),
+				Check: resource.ComposeAggregateTestCheckFunc(
+					testAccCheckServerlessCacheExists(ctx, resourceName, &serverlessElasticCache),
+					acctest.CheckResourceAttrRegionalARNFormat(ctx, resourceName, names.AttrARN, "elasticache", "serverlesscache:{name}"),
+					resource.TestCheckResourceAttr(resourceName, names.AttrName, rName),
+					resource.TestCheckResourceAttr(resourceName, names.AttrDescription, "test description updated"),
+				),
+			},
+		},
+	})
+}
+
 func TestAccElastiCacheServerlessCache_fullValkey(t *testing.T) {
 	ctx := acctest.Context(t)
 	if testing.Short() {
@@ -725,6 +765,43 @@ resource "aws_security_group" "test" {
 `, rName))
 }
 
+func testAccServerlessCacheConfig_redisUpdateWithUserGroup(rName, description string) string {
+	return acctest.ConfigCompose(acctest.ConfigVPCWithSubnets(rName, 2), fmt.Sprintf(`
+resource "aws_elasticache_user" "test" {
+  user_id       = "testuserid"
+  user_name     = "default"
+  access_string = "on ~* +@all"
+  engine        = "REDIS"
+  passwords     = ["password123456789"]
+}
+
+resource "aws_elasticache_user_group" "test" {
+  engine        = "REDIS"
+  user_group_id = "usergroupid"
+  user_ids      = [aws_elasticache_user.test.user_id]
+}
+
+resource "aws_elasticache_serverless_cache" "test" {
+  engine = "redis"
+  name   = %[1]q
+  cache_usage_limits {
+    data_storage {
+      maximum = 12
+      unit    = "GB"
+    }
+    ecpu_per_second {
+      maximum = 5100
+    }
+  }
+  daily_snapshot_time      = "09:00"
+  description              = %[2]q
+  major_engine_version     = "7"
+  snapshot_retention_limit = 1
+  user_group_id            = aws_elasticache_user_group.test.id
+}
+`, rName, description))
+}
+
 func testAccServerlessCacheConfig_fullValkey(rName string) string {
 	return acctest.ConfigCompose(acctest.ConfigVPCWithSubnets(rName, 2), fmt.Sprintf(`
 resource "aws_elasticache_serverless_cache" "test" {