Obsoletion request: '7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase activity' '5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase activity'

[pgaudet]

GO:0008397 sterol 12-alpha-hydroxylase activity (EC:1.14.14.139) has 2 children:
GO:0033779 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase activity
GO:0033778 5-beta-cholestane-3-alpha,7-alpha-diol 12-alpha-hydroxylase activity

These correspond to specific reactions in EC:1.14.14.139
Also, this EC corresponds to 3 RHEA reactions (ie, the 3 reactions defined in EC:1.14.14.139):

• RHEA:46752 | 7α-hydroxycholest-4-en-3-one + reduced [NADPH—hemoprotein reductase] + O2 = 7α,12α-dihydroxycholest-4-en-3-one + oxidized [NADPH—hemoprotein reductase] + H2O + H+  
• RHEA:65700 | chenodeoxycholate + reduced [NADPH—hemoprotein reductase] + O2 = cholate + oxidized [NADPH—hemoprotein reductase] + H2O + H+
• RHEA:15261 | 5β-cholestane-3α,7α-diol + reduced [NADPH—hemoprotein reductase] + O2 = 5β-cholestane-3α,7α,12α-triol + oxidized [NADPH—hemoprotein reductase] + H2O + H+

The same 4 proteins are annotated to these 3 terms, as these 3 reactions are catalyzed by the same enzyme, CYP8B1 (Q9UNU6 in human)

So with @nnouspikel and Lucila from RHEA we have agreed to merge these into the parent GO:0008397 sterol 12-alpha-hydroxylase activity.

There are 3 annotations, 2 UniProt, 1 RGD, that will automatically be re-mapped.