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Merge pull request #29169 from geneontology/issue-29152
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Obsoleted with replacement activating signal cointegrator 1 complex; …
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raymond91125 authored Nov 6, 2024
2 parents 0548eb2 + 7aa6382 commit a8fc762
Showing 1 changed file with 10 additions and 5 deletions.
15 changes: 10 additions & 5 deletions src/ontology/go-edit.obo
Original file line number Diff line number Diff line change
Expand Up @@ -425414,12 +425414,14 @@ intersection_of: part_of GO:0072583 ! clathrin-dependent endocytosis

[Term]
id: GO:0099053
name: activating signal cointegrator 1 complex
name: obsolete activating signal cointegrator 1 complex
namespace: cellular_component
def: "A protein complex that contains TRIP4 (ASC1) and acts a transcriptional coactivator by interacting with transcription factors such as NF-kappa B. In humans this complex has 4 subunits: TRIP4 + ASCC1-3." [PMID:12077347]
def: "OBSOLETE. A protein complex that contains TRIP4 (ASC1) and acts a transcriptional coactivator by interacting with transcription factors such as NF-kappa B. In humans this complex has 4 subunits: TRIP4 + ASCC1-3." [PMID:12077347]
comment: The reason for obsoletion is that this term is equivalent to GO:0180022 RQC-trigger complex.
synonym: "ASC-1 complex" EXACT [PMID:12077347]
is_a: GO:0090575 ! RNA polymerase II transcription regulator complex
relationship: capable_of GO:0003713 ! transcription coactivator activity
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29152" xsd:anyURI
is_obsolete: true
replaced_by: GO:0180022

[Term]
id: GO:0099054
Expand Down Expand Up @@ -467269,11 +467271,14 @@ creation_date: 2023-07-14T13:19:39Z
id: GO:0180022
name: RQC-trigger complex
namespace: cellular_component
def: "A ribosome disassembly complex which dissociates stalled ribsome subunits as part of the ribosome quality control pathway. RQT complex is composed of a RNA helicase-family protein yeast Rqt2 (human ASCC3), a ubiquitin-binding protein yeast Rqt3, (human ASCC2), and Rqt4 (Human TRIP4)." [PMID:28757607, PMID:32099016]
def: "A ribosome disassembly complex which dissociates stalled ribsome subunits as part of the ribosome quality control pathway. RQT complex is composed of a RNA helicase-family protein yeast Rqt2 (human ASCC3), a ubiquitin-binding protein yeast Rqt3, (human ASCC2), and Rqt4 (human TRIP4). The human complex has an additional component protein ASCC1 and can act as a transcriptional coactivator by interacting with transcription factors such as NF-kappa B." [PMID:12077347, PMID:28757607, PMID:32099016]
synonym: "activating signal cointegrator 1 complex" EXACT []
synonym: "ASC-1 complex" EXACT [PMID:12077347]
synonym: "RQT complex" EXACT []
is_a: GO:0032991 ! protein-containing complex
property_value: creation_date "2023-10-11T11:40:08Z" xsd:dateTime
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/26239" xsd:anyURI
property_value: term_tracker_item "https://github.com/geneontology/go-ontology/issues/29152" xsd:anyURI
created_by: vw

[Term]
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