Noble_1962_cellml.txt

def model Noble_1962 as
    def import using "Noble62_Na_channel.cellml" for
        comp Na_channel using comp sodium_channel;
    enddef;

    def import using "Noble62_K_channel.cellml" for
        comp K_channel using comp potassium_channel;
    enddef;

    def import using "Noble62_L_channel.cellml" for
        comp L_channel using comp leakage_channel;
    enddef;

    def import using "Noble62_units.cellml" for
        unit mV using unit mV;
        unit ms using unit ms;
        unit mM using unit mM;
        unit microF using unit microF;
        unit microA using unit microA;
        unit mS using unit mS;
    enddef;

    def import using "Noble62_parameters.cellml" for
        comp parameters using comp parameters;
    enddef;

    def map between parameters and membrane for
        vars Ki and Ki;
        vars Ko and Ko;
        vars Nai and Nai;
        vars Nao and Nao;
    enddef;

    def comp environment as
        var t: ms {init: 0, pub: out};
    enddef;

    def group as encapsulation for
        comp membrane incl
            comp Na_channel;
            comp K_channel;
            comp L_channel;
        endcomp;
    enddef;

    def comp membrane as
        var V: mV {init: -85, pub: out, priv: out};
        var t: ms {pub: in, priv: out};
        var Cm: microF {init: 12};
        var Ki: mM {pub: in, priv: out};
        var Ko: mM {pub: in, priv: out};
        var Nai: mM {pub: in, priv: out};
        var Nao: mM {pub: in, priv: out};
        var i_Na: microA {pub: out, priv: in};
        var i_K: microA {pub: out, priv: in};
        var i_L: microA {pub: out, priv: in};
        var g_Na: mS {priv: in};
        var h: dimensionless {priv: in};
        var m: dimensionless {priv: in};
        var g_K1: mS {priv: in};
        var g_K2: mS {priv: in};
        var n: dimensionless {priv: in};

        ode(V, t) = -(i_Na+i_K+i_L)/Cm;
    enddef;

    def map between membrane and environment for
        vars t and t;
    enddef;

    def map between Na_channel and membrane for
        vars V and V;
        vars t and t;
        vars Nai and Nai;
        vars Nao and Nao;
        vars i_Na and i_Na;
        vars g_Na and g_Na;
        vars h and h;
        vars m and m;
    enddef;

    def map between membrane and K_channel for
        vars V and V;
        vars t and t;
        vars Ki and Ki;
        vars Ko and Ko;
        vars i_K and i_K;
        vars g_K1 and g_K1;
        vars g_K2 and g_K2;
        vars n and n;
    enddef;

    def map between membrane and L_channel for
        vars V and V;
        vars i_L and i_L;
    enddef;
enddef;