diff --git a/cctbx/run_tests.py b/cctbx/run_tests.py
index f9d73dace3..e9902c3e24 100644
--- a/cctbx/run_tests.py
+++ b/cctbx/run_tests.py
@@ -56,7 +56,6 @@
   "$D/geometry_restraints/tst_process_nonbonded_proxies.py",
   "$D/geometry_restraints/tst_angle_derivs.py",
   "$D/geometry_restraints/tst_motif.py",
-  "$D/adp_restraints/tst_ext.py",
   "$D/regression/tst_math_module.py",
   ["$D/regression/tst_krivy_gruber.py", "--Quick"],
   "$D/regression/tst_sgtbx.py",
@@ -101,7 +100,6 @@
   "$D/maptbx/tst_real_space_refinement_simple.py",
   "$D/maptbx/tst_interpolation.py",
   "$D/maptbx/tst_interpolation_2.py",
-  "$D/regression/tst_loc_res.py",
   "$D/maptbx/tst_target_and_gradients.py",
   ["$D/regression/tst_miller_merge_equivalents.py", "P31"],
   ["$D/regression/tst_grouped_data.py", "P31"],
@@ -152,7 +150,6 @@
    "$D/regression/tst_connectivity.py",
    "$D/regression/tst_connectivity_allsym.py",
    "$D/regression/tst_diffuse.py",
-   "$D/regression/tst_grm_modifications.py",
    "$D/regression/tst_prepare_map_for_docking.py",
    "$D/regression/tst_wavelength_units.py",
   ]
diff --git a/iotbx/run_tests.py b/iotbx/run_tests.py
index e477512a51..b03ffac1d2 100644
--- a/iotbx/run_tests.py
+++ b/iotbx/run_tests.py
@@ -38,7 +38,6 @@
   "$D/cif/tests/tst_geometry.py",
   "$D/cif/tests/tst_lex_parse_build.py",
   "$D/cif/tests/tst_model.py",
-  "$D/cif/tests/tst_restraints.py",
   "$D/cif/tests/tst_validation.py",
   "$D/cif/tests/tst_ucif_examples_compilation.py",
   "$D/cif/tests/tst_parser.py",
@@ -114,7 +113,6 @@
   "$D/regression/tst_reflection_file_editor.py",
   "$D/regression/tst_split_models.py",
   "$D/regression/tst_pdb_as_fasta.py",
-  "$D/regression/tst_pdb_link_records.py",
   "$D/regression/tst_merging_statistics.py",
   "$D/regression/tst_simple_map_coefficients.py",
   "$D/regression/tst_sort_atoms.py",
@@ -144,7 +142,6 @@
   "$D/bioinformatics/test/tst_alignment_as_hsearch.py",
   "$D/bioinformatics/test/tst_ebi_wu_blast_xml.py",
   "$D/bioinformatics/test/tst_ncbi_blast_xml.py",
-  "$D/bioinformatics/pdb_info.py",
   "$D/regression/tst_cif_as_pdb_1atom.py",
   "$D/regression/tst_cif_1.py",
   "$D/regression/tst_split_data_cif.py",