diff --git a/Yank/experiment.py b/Yank/experiment.py
index 8ef5cbe2..b5a42063 100644
--- a/Yank/experiment.py
+++ b/Yank/experiment.py
@@ -1659,6 +1659,7 @@ def _is_pipeline_solvent_with_receptor(field, solvent_id, error):
             schema:
                 type: string
                 validator: file_exists
+            dependencies: phase2_path
             validator: supported_system_files
         phase2_path:
             required: no