diff --git a/pymbar/tests/test_mbar_solvers.py b/pymbar/tests/test_mbar_solvers.py
index 0ec9aee9..121eea43 100644
--- a/pymbar/tests/test_mbar_solvers.py
+++ b/pymbar/tests/test_mbar_solvers.py
@@ -64,7 +64,7 @@ def run_mbar_protocol(oscillator_bundle, protocol):
         "CG",
         "BFGS",
         "Newton-CG",
-        "TNC",
+        pytest.param("TNC", marks=pytest.mark.flaky(max_runs=2)),  # This one is flaky
         "trust-ncg",
         "trust-krylov",
         "trust-exact",