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molecular_entity-config.yaml
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molecular_entity-config.yaml
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description: A gene, gene product, small molecule or macromolecule (including protein
complex)
display_name: !!python/object/new:biolinkml.meta.ClassDefinitionName
- molecular entity
document_category: !!python/object/new:biolinkml.meta.ClassDefinitionName
- molecular entity
fields:
- description: A unique identifier for a thing. Must be either a CURIE shorthand for
a URI or a complete URI
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- id
id: id
- description: A human-readable name for a thing
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- name
id: name
- cardinality: multi
description: Name of the high level ontology class in which this entity is categorized.
Corresponds to the label for the biolink entity type class. In a neo4j database
this MAY correspond to the neo4j label tag
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- category
id: category
- cardinality: multi
description: A relationship that is asserted between two named things
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- related to
id: related_to
- cardinality: multi
description: holds between any two entities that directly or indirectly interact
with each other
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- interacts with
id: interacts_with
- description: A grouping for any property that holds between a node and a value
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- node property
id: node_property
- description: An IRI for the node. This is determined by the id using expansion rules.
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- iri
id: iri
- cardinality: multi
description: Alternate human-readable names for a thing
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- synonym
id: synonym
- description: a long-form human readable name for a thing
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- full name
id: full_name
- description: a human-readable description of a thing
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- description
id: description
- cardinality: multi
description: more commonly used for gene symbols in yeast
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- systematic synonym
id: systematic_synonym
- cardinality: multi
description: holds between a biological entity and a phenotype, where a phenotype
is construed broadly as any kind of quality of an organism part, a collection
of these qualities, or a change in quality or qualities (e.g. abnormally increased
temperature).
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- has phenotype
id: has_phenotype
- cardinality: multi
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- molecularly interacts with
id: molecularly_interacts_with
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one changes the amount of the other within a system of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- affects abundance of
id: affects_abundance_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one increases the amount of the other within a system of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- increases abundance of
id: increases_abundance_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one decreases the amount of the other within a system of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- decreases abundance of
id: decreases_abundance_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one changes the activity of the other within a system of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- affects activity of
id: affects_activity_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one increases the activity of the other within a system of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- increases activity of
id: increases_activity_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one decreases the activity of the other within a system of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- decreases activity of
id: decreases_activity_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one changes the level of expression of the other within a system of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- affects expression of
id: affects_expression_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one increases the level of expression of the other within a system of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- increases expression of
id: increases_expression_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one decreases the level of expression of the other within a system of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- decreases expression of
id: decreases_expression_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one changes the rate or quality of folding of the other
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- affects folding of
id: affects_folding_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one increases the rate or quality of folding of the other
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- increases folding of
id: increases_folding_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one decreases the rate or quality of folding of the other
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- decreases folding of
id: decreases_folding_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one changes the localization of the other within a system of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- affects localization of
id: affects_localization_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one increases the proper localization of the other within a system of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- increases localization of
id: increases_localization_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one decreases the proper localization of the other within a system of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- decreases localization of
id: decreases_localization_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one impacts the metabolic processing of the other within a system of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- affects metabolic processing of
id: affects_metabolic_processing_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one increases the rate of metabolic processing of the other within a system of
interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- increases metabolic processing of
id: increases_metabolic_processing_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one decreases the rate of metabolic processing of the other within a system of
interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- decreases metabolic processing of
id: decreases_metabolic_processing_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one leads changes in the molecular modification(s) of the other (e.g. via post-translational
modifications of proteins such as the addition of phosphoryl group, or via redox
reaction that adds or subtracts electrons)
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- affects molecular modification of
id: affects_molecular_modification_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one leads to increased molecular modification(s) of the other (e.g. via post-translational
modifications of proteins such as the addition of phosphoryl group, or via redox
reaction that adds or subtracts electrons)
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- increases molecular modification of
id: increases_molecular_modification_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one leads to decreased molecular modification(s) of the other (e.g. via post-translational
modifications of proteins such as the addition of phosphoryl group, or via redox
reaction that adds or subtracts electrons)
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- decreases molecular modification of
id: decreases_molecular_modification_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one impacts the rate of chemical synthesis of the other
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- affects synthesis of
id: affects_synthesis_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one increases the rate of chemical synthesis of the other
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- increases synthesis of
id: increases_synthesis_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one decreases the rate of chemical synthesis of the other
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- decreases synthesis of
id: decreases_synthesis_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one impacts the rate of degradation of the other within a system of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- affects degradation of
id: affects_degradation_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one increases the rate of degradation of the other within a system of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- increases degradation of
id: increases_degradation_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one decreases the rate of degradation of the other within a system of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- decreases degradation of
id: decreases_degradation_of
- cardinality: multi
description: holds between a molecular entity and a genomic entity where the action
or effect of the molecular entity impacts the rate of mutation of the genomic
entity within a system of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- affects mutation rate of
id: affects_mutation_rate_of
- cardinality: multi
description: holds between a molecular entity and a genomic entity where the action
or effect of the molecular entity increases the rate of mutation of the genomic
entity within a system of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- increases mutation rate of
id: increases_mutation_rate_of
- cardinality: multi
description: holds between a molecular entity and a genomic entity where the action
or effect of the molecular entity decreases the rate of mutation of the genomic
entity within a system of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- decreases mutation rate of
id: decreases_mutation_rate_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one impacts the susceptibility of a biological entity or system (e.g. an organism,
cell, cellular component, macromolecular machine, biological or pathological process)
to the other
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- affects response to
id: affects_response_to
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one increases the susceptibility of a biological entity or system (e.g. an organism,
cell, cellular component, macromolecular machine, biological or pathological process)
to the other
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- increases response to
id: increases_response_to
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one decreases the susceptibility of a biological entity or system (e.g. an organism,
cell, cellular component, macromolecular machine, biological or pathological process)
to the other
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- decreases response to
id: decreases_response_to
- cardinality: multi
description: holds between a molecular entity and an mRNA where the action or effect
of the molecular entity impacts the splicing of the mRNA
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- affects splicing of
id: affects_splicing_of
- cardinality: multi
description: holds between a molecular entity and an mRNA where the action or effect
of the molecular entity increases the proper splicing of the mRNA
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- increases splicing of
id: increases_splicing_of
- cardinality: multi
description: holds between a molecular entity and an mRNA where the action or effect
of the molecular entity decreases the proper splicing of the mRNA
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- decreases splicing of
id: decreases_splicing_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one impacts the stability of the other within a system of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- affects stability of
id: affects_stability_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one increases the stability of the other within a system of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- increases stability of
id: increases_stability_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one decreases the stability of the other within a system of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- decreases stability of
id: decreases_stability_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one impacts the rate of transport of the other across some boundary in a system
of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- affects transport of
id: affects_transport_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one increases the rate of transport of the other across some boundary in a system
of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- increases transport of
id: increases_transport_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one decreases the rate of transport of the other across some boundary in a system
of interest
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- decreases transport of
id: decreases_transport_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one impacts the rate of secretion of the other out of a cell, gland, or organ
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- affects secretion of
id: affects_secretion_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one increases the rate of secretion of the other out of a cell, gland, or organ
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- increases secretion of
id: increases_secretion_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one decreases the rate of secretion of the other out of a cell, gland, or organ
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- decreases secretion of
id: decreases_secretion_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one impacts the rate of uptake of the other into of a cell, gland, or organ
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- affects uptake of
id: affects_uptake_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one increases the rate of uptake of the other into of a cell, gland, or organ
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- increases uptake of
id: increases_uptake_of
- cardinality: multi
description: holds between two molecular entities where the action or effect of
one decreases the rate of uptake of the other into of a cell, gland, or organ
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- decreases uptake of
id: decreases_uptake_of
- cardinality: multi
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- regulates, entity to entity
id: regulates_entity_to_entity
- cardinality: multi
description: holds between a measurable molecular entity and a disease or phenotypic
feature, where the entity is used as an indicator of the presence or state of
the disease or feature.
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- biomarker for
id: biomarker_for
- cardinality: multi
description: connects a thing to a class representing a taxon
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- in taxon
id: in_taxon
- cardinality: multi
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- positively regulates, entity to entity
id: positively_regulates_entity_to_entity
- cardinality: multi
display_name: !!python/object/new:biolinkml.meta.SlotDefinitionName
- negatively regulates, entity to entity
id: negatively_regulates_entity_to_entity
id: molecular_entity
schema_generating: true
weight: 20