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QC approaches #2

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petermchale opened this issue Nov 15, 2024 · 1 comment
Open

QC approaches #2

petermchale opened this issue Nov 15, 2024 · 1 comment

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@petermchale
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This video describes a number of QC steps that are implemented in an R package. Are these also implemented in mepylome? Thanks.

  • probe "masking"
  • pOOBAH
  • dyeBiasNL
@brj0
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brj0 commented Nov 15, 2024

Mepylome incorporates three preprocessing methods—Illumina, SWAN, and NOOB—which include dye correction and out-of-band background correction (see MethylData in beads.py). However, it currently lacks QC checks and probe masking functionality.

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