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Can we use it on several daatsets for which we're not sure about the normalization #145

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Sophon-0 opened this issue Apr 12, 2023 · 0 comments

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@Sophon-0
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Hello,

  1. I have a few single cell datasets that have been normalized in different ways. some are log2 TPM, some are raw counts, and some are probably just log2 raw count. I don't even know myself. Can we use scanorama on these ?

  2. The output of scanorama is a low dimensional embedding. Which means that the data are actually not integrated at the gene expression level. What other methods do you recommend for this type of tasks ? I would really like to have corrected datasets at expression level.
    Thanks !

@Sophon-0 Sophon-0 changed the title Can we use it on several daatsets for we're not sure about the normalization Can we use it on several daatsets for which we're not sure about the normalization Apr 12, 2023
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