diff --git a/test/filters/browser_tests.filter b/test/filters/browser_tests.filter
index 7405a7596819..3a8eee6d6092 100644
--- a/test/filters/browser_tests.filter
+++ b/test/filters/browser_tests.filter
@@ -58,14 +58,14 @@
 -ThreatDOMDetailsTest.CheckTagAndAttributeListIsSorted
 
 # Optimization Guide is disabled
--All/UserAnnotationsServiceBrowserTest.*/*
--All/UserAnnotationsServiceExplicitAllowlistBrowserTest.*/*
 -ChromeRenderFrameObserverTest.OptGuideGetsText
 -DependencyParserModelLoaderBrowserTest.*
 -HistoryEmbeddingsRestrictedSigninBrowserTest.SearchDoesNotReceiveAnswerForRestrictedSignin
 -OptimizationGuideInternalsPageBrowserTest.*
 -OptimizationGuideKeyedServiceBrowserTest.*
 -OptimizationGuideKeyedServiceEnterpriseBrowserTest.*
+-UserAnnotationsServiceBrowserTest.*
+-UserAnnotationsServiceExplicitAllowlistBrowserTest.*
 -VisualQueryClassifierAgentTest.StartClassification_InvalidModel
 -VisualQueryClassifierAgentTest.StartClassification_NoImages
 -VisualQueryClassifierAgentTest.StartClassification_SingleImageNonShoppy
@@ -297,6 +297,7 @@
 -All/WebAppLinkCapturingParameterizedBrowserTest.CheckLinkCaptureCombinations/*
 -Capturable/WebAppLinkCapturingParameterizedBrowserTest.*
 -Redirection_BackgroundDisposition/WebAppLinkCapturingParameterizedBrowserTest.*
+-Redirection_Capturable_Reparenting/WebAppLinkCapturingParameterizedBrowserTest.*/*
 -Redirection_NavigateCurrent/WebAppLinkCapturingParameterizedBrowserTest.CheckLinkCaptureCombinations/CaptureOn_AppWnd_ScopeA2B_ServerSideViaB_ViaLink_MiddleClick_WithOpener_TargetBlank
 -Redirection_NavigateCurrent/WebAppLinkCapturingParameterizedBrowserTest.CheckLinkCaptureCombinations/CaptureOn_AppWnd_ScopeA2B_ServerSideViaB_ViaLink_ShiftClick_WithOpener_TargetBlank
 -Redirection_OpenInApp_NewWindowDisposition/WebAppLinkCapturingParameterizedBrowserTest.*
@@ -799,6 +800,7 @@
 -All/PredictionManagerBrowserTest.*/*
 -All/PredictionManagerModelDownloadingBrowserTest.*
 -All/PredictionManagerModelDownloadingBrowserTest.*/*
+-LCPPPrefetchSubresourceTest.Base
 -LoadingPredictorBrowserTest.*
 -LoadingPredictorBrowserTestWithNoLocalPredictions.*
 -LoadingPredictorBrowserTestWithOptimizationGuide.*
@@ -1693,6 +1695,7 @@
 -ControlledFrameAvailabilityTest.Verify/*
 -ControlledFrameAvailableChannels/*
 -ControlledFrameDialogBrowserTest.*/*
+-ControlledFrameDisabledPermissionFileSystemAccessTest.*/*
 -ControlledFrameDisabledPermissionSerialTest.WebSerial/*
 -ControlledFrameDisabledPermissionUsbTest.WebUSB/*
 -ControlledFrameDisabledPermissionWebBluetoothTest.WebBluetooth/*
@@ -1838,6 +1841,7 @@
 # they try to call showOpenFilePicker
 -FileSystemObserverStorageAccessTest.StateChangeFromAllowedToBlocked
 -FileSystemObserverStorageAccessTest.StorageAccess*
+-WebViewFileSystemAccessTest.Shim_TestEnabledInTabAndWebView
 
 # This test is disabled because it fails when it encounters unrecognized (Brave)
 # WebUI URL hashes.
@@ -1879,6 +1883,11 @@
 -LiveCaptionAutomaticLanguageDownloadTest.*
 -LiveCaptionControllerTest.*
 
+# These tests crash because we disable
+# user_education::features::kWhatsNewVersion2
+-WhatsNewFetcherMultipleCustomizationsBrowserTest.GetV2ServerURLForRender
+-WhatsNewFetcherOneCustomizationBrowserTest.GetV2ServerURLForRender
+
 # Tests below this point have not been diagnosed or had issues created yet.
 -_/WebrtcLoggingPrivateApiStartEventLoggingTestFeatureAndPolicyEnabled.*
 -AccessCodeCastHandlerBrowserTest.*
diff --git a/test/filters/unit_tests.filter b/test/filters/unit_tests.filter
index 13d883ff4cb1..ae8c78170fdb 100644
--- a/test/filters/unit_tests.filter
+++ b/test/filters/unit_tests.filter
@@ -29,7 +29,7 @@
 -MV2/ExtensionProtocolsTest.MetadataFolder/0
 -MV3/ExtensionProtocolsTest.MetadataFolder/0
 
-# These tests fail because sync_helper::IsSyncable(extension) resturns false
+# These tests fail because sync_helper::IsSyncable(extension) returns false
 # due to UPDATER_DEV_ENDPOINT being empty and not matching expected store URL.
 -ExtensionSyncServiceCustomGalleryTest.ProcessSyncDataDeferredEnable
 -ExtensionSyncServiceCustomGalleryTest.ProcessSyncDataPermissionApproval
@@ -361,6 +361,7 @@
 -ChromeAutofillPredictionImprovementsClientTest.EligibilityOfSignedInUserWithMlEnabled
 -EnclaveAuthenticatorRequestDelegateTest.BrowserProvidedPasskeysAvailable
 -EnclaveManagerTest.PrimaryUserChange
+-ExtensionSyncServiceTransportModeTest.OnlySyncAccountExtensions
 -ManagePasswordsUIControllerWithBrowserTestExplicitBrowserSignin.MovePasswordUponSigninWithExistingAccount
 -PeopleHandlerDiceTest.StoredAccountsList
 -PeopleHandlerDiceUnifiedConsentTest.StoredAccountsList
@@ -503,6 +504,7 @@
 # https://issues.chromium.org/issues/41484323
 -TabSearchPageHandlerDeclutterTest.TabDeclutterFindStaleTabs
 -TabSearchPageHandlerDeclutterTest.TabDeclutterObserverTest
+-TabSearchPageHandlerDeclutterTest.TabDeclutterStaleTabChanges
 
 # This test fails because we insert our own bookmarks submenu into the app menu
 # model
@@ -1043,6 +1045,7 @@
 -ThemeProviderRedirectedEquivalenceTest.*
 -ThemeServiceTest.*
 -ThemeSyncableServiceTest.*
+-ThemeSyncableServiceTestWithAccountThemesSeparation.LoadsLocalGrayscaleThemeFromPrefUponSyncStop
 -ThemeSyncableServiceWithMigrationFlag*.*
 -ToolbarActionsModelUnitTest.*
 -TranslateManagerRenderViewHostTest.*