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PPI ensembles #10

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sacombs opened this issue Mar 5, 2024 · 3 comments
Open

PPI ensembles #10

sacombs opened this issue Mar 5, 2024 · 3 comments

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@sacombs
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sacombs commented Mar 5, 2024

Any chance to adopt this for protein-protein interfaces?
@ajfriedman22
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I would also be interested in adopting this for multimers.

@eunos-1128
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eunos-1128 commented Mar 19, 2024 •
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I'm also interested in application to multimers.

Methods sampling conformations with MSA subsampling so far are not applicable to PPI because of their shallow MSA, which leads to insufficient coevolutionary information.

Really interested if alphaflow works for multimers.

@amelie-iska
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Same.

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@sacombs @eunos-1128 @ajfriedman22 @amelie-iska