diff --git a/.changeset/purple-news-do.md b/.changeset/purple-news-do.md
new file mode 100644
index 0000000000..4c64d168bb
--- /dev/null
+++ b/.changeset/purple-news-do.md
@@ -0,0 +1,5 @@
+---
+'@aws-amplify/backend-deployer': patch
+---
+
+Catches most common EPERM error and update to resolution message for stack in failed state
diff --git a/packages/backend-deployer/src/cdk_error_mapper.test.ts b/packages/backend-deployer/src/cdk_error_mapper.test.ts
index 3850467a35..a4f9d4952b 100644
--- a/packages/backend-deployer/src/cdk_error_mapper.test.ts
+++ b/packages/backend-deployer/src/cdk_error_mapper.test.ts
@@ -359,6 +359,12 @@ const testErrorMappings = [
     errorName: 'FilePermissionsError',
     expectedDownstreamErrorMessage: `EACCES: permission denied, unlink '.amplify/artifacts/cdk.out/synth.lock'`,
   },
+  {
+    errorMessage: `EPERM: operation not permitted, rename 'C:/Users/someUser/amplify/artifacts/cdk.out/synth.lock.6785_1' → 'C:/Users/someUser/amplify/artifacts/cdk.out/synth.lock'`,
+    expectedTopLevelErrorMessage: `Not permitted to rename file: 'C:/Users/someUser/amplify/artifacts/cdk.out/synth.lock.6785_1'`,
+    errorName: 'FilePermissionsError',
+    expectedDownstreamErrorMessage: undefined,
+  },
   {
     errorMessage: `This CDK CLI is not compatible with the CDK library used by your application. Please upgrade the CLI to the latest version.
       (Cloud assembly schema version mismatch: Maximum schema version supported is 36.0.0, but found 36.1.1)`,
diff --git a/packages/backend-deployer/src/cdk_error_mapper.ts b/packages/backend-deployer/src/cdk_error_mapper.ts
index 949a9212f3..5b121ea673 100644
--- a/packages/backend-deployer/src/cdk_error_mapper.ts
+++ b/packages/backend-deployer/src/cdk_error_mapper.ts
@@ -184,6 +184,14 @@ export class CdkErrorMapper {
       errorName: 'FilePermissionsError',
       classification: 'ERROR',
     },
+    {
+      errorRegex:
+        /EPERM: operation not permitted, rename (?<fileName>(.*)\/synth\.lock\.\S+) → '(.*)\/synth\.lock'/,
+      humanReadableErrorMessage: 'Not permitted to rename file: {fileName}',
+      resolutionMessage: `Try running the command again and ensure that only one instance of sandbox is running. If it still doesn't work check the permissions of '.amplify' folder`,
+      errorName: 'FilePermissionsError',
+      classification: 'ERROR',
+    },
     {
       errorRegex: new RegExp(
         `\\[ERR_MODULE_NOT_FOUND\\]:(.*)${this.multiLineEolRegex}|Error: Cannot find module (.*)`
@@ -220,7 +228,7 @@ export class CdkErrorMapper {
       humanReadableErrorMessage:
         'The CloudFormation deletion failed due to {stackName} being in DELETE_FAILED state. Ensure all your resources are able to be deleted',
       resolutionMessage:
-        'The following resource(s) failed to delete: {resources}. Ensure they are in a state where they can be deleted. Find more information in the CloudFormation AWS Console for this stack.',
+        'The following resource(s) failed to delete: {resources}. Check the error message for more details and ensure your resources are in a state where they can be deleted. Check the CloudFormation AWS Console for this stack to find additional information.',
       errorName: 'CloudFormationDeletionError',
       classification: 'ERROR',
     },