diff --git a/hw/mcu/nordic/nrf52xxx/syscfg.yml b/hw/mcu/nordic/nrf52xxx/syscfg.yml
index d28e2d8d7b..1f15b43d63 100644
--- a/hw/mcu/nordic/nrf52xxx/syscfg.yml
+++ b/hw/mcu/nordic/nrf52xxx/syscfg.yml
@@ -495,16 +495,16 @@ syscfg.vals.XTAL_32768_SYNTH:
     MCU_LFCLK_SOURCE: LFSYNTH
 
 syscfg.restrictions:
-    - "!I2C_0 || (I2C_0_PIN_SCL && I2C_0_PIN_SDA)"
-    - "!I2C_1 || (I2C_1_PIN_SCL && I2C_1_PIN_SDA)"
-    - "!SPI_0_MASTER || (SPI_0_MASTER_PIN_SCK && SPI_0_MASTER_PIN_MOSI && SPI_0_MASTER_PIN_MISO)"
-    - "!SPI_1_MASTER || (SPI_1_MASTER_PIN_SCK && SPI_1_MASTER_PIN_MOSI && SPI_1_MASTER_PIN_MISO)"
-    - "!SPI_2_MASTER || (SPI_2_MASTER_PIN_SCK && SPI_2_MASTER_PIN_MOSI && SPI_2_MASTER_PIN_MISO)"
-    - "!SPI_3_MASTER || (SPI_3_MASTER_PIN_SCK && SPI_3_MASTER_PIN_MOSI && SPI_3_MASTER_PIN_MISO)"
-    - "!SPI_0_SLAVE || (SPI_0_SLAVE_PIN_SCK && SPI_0_SLAVE_PIN_MOSI && SPI_0_SLAVE_PIN_MISO && SPI_0_SLAVE_PIN_SS)"
-    - "!SPI_1_SLAVE || (SPI_1_SLAVE_PIN_SCK && SPI_1_SLAVE_PIN_MOSI && SPI_1_SLAVE_PIN_MISO && SPI_1_SLAVE_PIN_SS)"
-    - "!SPI_2_SLAVE || (SPI_2_SLAVE_PIN_SCK && SPI_2_SLAVE_PIN_MOSI && SPI_2_SLAVE_PIN_MISO && SPI_2_SLAVE_PIN_SS)"
-    - "!UART_0 || (UART_0_PIN_TX && UART_0_PIN_RX)"
-    - "!UART_1 || (UART_1_PIN_TX && UART_1_PIN_RX)"
+    - "!I2C_0 || (I2C_0_PIN_SCL != \"\" && I2C_0_PIN_SDA != \"\")"
+    - "!I2C_1 || (I2C_1_PIN_SCL != \"\" && I2C_1_PIN_SDA != \"\")"
+    - "!SPI_0_MASTER || (SPI_0_MASTER_PIN_SCK != \"\" && SPI_0_MASTER_PIN_MOSI != \"\" && SPI_0_MASTER_PIN_MISO != \"\")"
+    - "!SPI_1_MASTER || (SPI_1_MASTER_PIN_SCK != \"\" && SPI_1_MASTER_PIN_MOSI != \"\" && SPI_1_MASTER_PIN_MISO != \"\")"
+    - "!SPI_2_MASTER || (SPI_2_MASTER_PIN_SCK != \"\" && SPI_2_MASTER_PIN_MOSI != \"\" && SPI_2_MASTER_PIN_MISO != \"\")"
+    - "!SPI_3_MASTER || (SPI_3_MASTER_PIN_SCK != \"\" && SPI_3_MASTER_PIN_MOSI != \"\" && SPI_3_MASTER_PIN_MISO != \"\")"
+    - "!SPI_0_SLAVE || (SPI_0_SLAVE_PIN_SCK != \"\" && SPI_0_SLAVE_PIN_MOSI != \"\" && SPI_0_SLAVE_PIN_MISO != \"\" && SPI_0_SLAVE_PIN_SS != \"\")"
+    - "!SPI_1_SLAVE || (SPI_1_SLAVE_PIN_SCK != \"\" && SPI_1_SLAVE_PIN_MOSI != \"\" && SPI_1_SLAVE_PIN_MISO != \"\" && SPI_1_SLAVE_PIN_SS != \"\")"
+    - "!SPI_2_SLAVE || (SPI_2_SLAVE_PIN_SCK != \"\" && SPI_2_SLAVE_PIN_MOSI != \"\" && SPI_2_SLAVE_PIN_MISO != \"\" && SPI_2_SLAVE_PIN_SS != \"\")"
+    - "!UART_0 || (UART_0_PIN_TX != \"\" && UART_0_PIN_RX != \"\")"
+    - "!UART_1 || (UART_1_PIN_TX != \"\" && UART_1_PIN_RX != \"\")"
     - "(OS_TICKS_PER_SEC == 128 || OS_TICKS_PER_SEC == 256 || OS_TICKS_PER_SEC == 512 || OS_TICKS_PER_SEC == 1024)"